18265-75-3

Basic information

• Product Name: 1-(2-HYDROXYPHENYL)PROPAN-1-ONE OXIME
• Synonyms: 1-(2-HYDROXYPHENYL)PROPAN-1-ONE OXIME
• CAS NO: 18265-75-3
• Molecular Formula: C₉H₁₁NO₂
• Molecular Weight: 165.19
• Mol File: 18265-75-3.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-(2-HYDROXYPHENYL)PROPAN-1-ONE OXIME(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-HYDROXYPHENYL)PROPAN-1-ONE OXIME(18265-75-3)
• EPA Substance Registry System: 1-(2-HYDROXYPHENYL)PROPAN-1-ONE OXIME(18265-75-3)

Safety Data

• Hazardous Substances Data: 18265-75-3(Hazardous Substances Data)

Usage

General Description

1-(2-Hydroxyphenyl)propan-1-one oxime, also known as acetophenone oxime, is a chemical compound with the molecular formula C9H11NO. It is a white crystalline solid that is commonly used as a chemical intermediate in the production of various pharmaceuticals and agrochemicals. Acetophenone oxime is also used as a chelating agent and an anti-scaling agent in water treatment applications. Additionally, it has been studied for its potential antioxidant and antimicrobial properties. However, the compound may pose environmental and health risks, and caution should be exercised in its handling and disposal.

Upstream product

• 610-99-1 1-(2-Hydroxy-phenyl)-propan-1-on 

Downstream Products

• 1202040-27-4 [Mn₃O(OC₆H₄C(Et)=NO)3(O₂CC₆H₅)2(triethanolamine(+1H))(H₂O)2] 
• 6963-37-7 propionic acid-(2-hydroxy-anilide) 
• 1235278-81-5 [Mn₆O₂(Et-sao)6(O₂P(Ph)2)2(MeOH)6] 
• 1235278-88-2 [Mn₆O₂(Et-sao)6(O₂PHPh)2(MeOH)6]*MeOH 

Relevant articles and documents

Zero-field splitting in {MnIII3(μ3-O)} core single-molecule magnets investigated by inelastic neutron scattering and high-field electron paramagnetic resonance spectroscopy

The global zero-field splitting (ZFS) parameters of three, ferromagnetically coupled, μ3-κ3-[XO4]- (X = Cl, Re) capped, manganese(III) oximate single-molecule magnets, [Mn3O(R-sao)3(2,4′-bipyridine)3XO4] [X = Cl, R = Me, Et; X = Re, R = Me; Me-sao = 2-hydroxyphenylethanone oximate(2-)], with crystallographic trigonal symmetry were determined by use of inelastic neutron scattering and high-field/high-frequency electron paramagnetic resonance spectroscopy. ReO4- (O...O ca. 1.7 ?) is larger than ClO4- (O...O ca. 1.4 ?), which allows more parallel alignment of the local ZFS tensors. However, this chemical modification results in concomitant distortions in the equatorial ligand plane. Consistent parametrization of all spectroscopic data was achieved, and effective spin-reversal barriers determined from alternating current susceptibility data were shown to be in good accordance with the energy barriers deduced from spectroscopy.

Synthesis of 1,2-benzisoxazole 2-oxides

(Chemical Equation Presented) A series of 2-hydroxyaryl ketoximes were converted to the corresponding 1,2- benzisoxazole 2-oxides by treatment with iodobenzene diacetate (in acetic acid or methanol) or N-chlorosuccinimide in water. Both methods gave moderate to excellent yields for a variety of substituted oximes under mild conditions within short reaction times. The latter method has the advantages of an aqueous solvent and lack of halogenated organic by-products. Copyright Taylor & Francis Group, LLC.

1,2-Benzisoxazole Phosphorodiamidates as Novel Anticancer Prodrugs Requiring Bioreductive Activation

Several 1,2-benzisoxazole phosphorodiamidates have been designed as prodrugs of phosphoramide mustard requiring bioreductive activation. Enzymatic reduction of 1,2-benziosoxazole moiety is expected to result in the formation of imine intermediate due to t