18265-75-3

Usage

Uses

Used in Pharmaceutical and Agrochemical Industries:
1-(2-Hydroxyphenyl)propan-1-one oxime is used as a chemical intermediate for the production of various pharmaceuticals and agrochemicals. Its role in these applications stems from its ability to serve as a building block for the synthesis of a wide range of compounds with therapeutic and pesticidal properties.
Used in Water Treatment Applications:
In the water treatment industry, 1-(2-Hydroxyphenyl)propan-1-one oxime is utilized as a chelating agent and an anti-scaling agent. Its chelating properties enable it to bind with metal ions, preventing the formation of insoluble salts that can cause scaling and fouling in water systems. This function is crucial for maintaining the efficiency and longevity of water treatment equipment.
Used in Antioxidant and Antimicrobial Applications:
Although still under investigation, 1-(2-Hydroxyphenyl)propan-1-one oxime has shown potential as an antioxidant and antimicrobial agent. Its antioxidant properties could be harnessed to protect against oxidative stress and related conditions, while its antimicrobial potential may be useful in combating microbial growth in various settings. Further research is needed to fully understand and optimize these applications.

Upstream product

• 610-99-1 1-(2-Hydroxy-phenyl)-propan-1-on 

Downstream Products

• 6797-13-3 2-ethyl-1,3-benzoxazole 
• 1202040-27-4 [Mn₃O(OC₆H₄C(Et)=NO)3(O₂CC₆H₅)2(triethanolamine(+1H))(H₂O)2] 
• 201941-50-6 [Cu(S₂CN(CH₂C₆H₅)2)(OC₆H₄C(CH₂CH₃)(NOH))] 
• 75633-00-0 3-ethyl-1,2-benzisoxazole 2-oxide 
• 6963-37-7 propionic acid-(2-hydroxy-anilide) 
• 1235278-81-5 [Mn₆O₂(Et-sao)6(O₂P(Ph)2)2(MeOH)6] 
• 1235278-88-2 [Mn₆O₂(Et-sao)6(O₂PHPh)2(MeOH)6]*MeOH 

Relevant academic research and scientific papers

Zero-field splitting in {MnIII3(μ3-O)} core single-molecule magnets investigated by inelastic neutron scattering and high-field electron paramagnetic resonance spectroscopy

The global zero-field splitting (ZFS) parameters of three, ferromagnetically coupled, μ3-κ3-[XO4]- (X = Cl, Re) capped, manganese(III) oximate single-molecule magnets, [Mn3O(R-sao)3(2,4′-bipyridine)3XO4] [X = Cl, R = Me, Et; X = Re, R = Me; Me-sao = 2-hydroxyphenylethanone oximate(2-)], with crystallographic trigonal symmetry were determined by use of inelastic neutron scattering and high-field/high-frequency electron paramagnetic resonance spectroscopy. ReO4- (O...O ca. 1.7 ?) is larger than ClO4- (O...O ca. 1.4 ?), which allows more parallel alignment of the local ZFS tensors. However, this chemical modification results in concomitant distortions in the equatorial ligand plane. Consistent parametrization of all spectroscopic data was achieved, and effective spin-reversal barriers determined from alternating current susceptibility data were shown to be in good accordance with the energy barriers deduced from spectroscopy.

From antiferromagnetic to ferromagnetic exchange in a family of oxime-based MnIII dimers: A magneto-structural study

The reaction of Mn(ClO4)2·6H2O, a derivatised phenolic oxime (R-saoH2) and the ligand tris(2-pyridylmethyl)amine (tpa) in a basic alcoholic solution leads to the formation of a family of cluster compounds of general formula [Mn III2O(R-sao)(tpa)2](ClO4) 2 (1, R = H; 2, R = Me; 3, R = Et; 4, R = Ph). The structure is that of a simple, albeit asymmetric, dimer of two MnIII ions bridged through one μ-O2- ion and the -N-O- moiety of the phenolic oxime. Magnetometry reveals that the exchange interaction between the two Mn III ions in complexes 1, 3 and 4 is antiferromagnetic, but that for complex 2 is ferromagnetic. A theoretically developed magneto-structural correlation reveals that the dominant structural parameter influencing the sign and magnitude of the pairwise interaction is the dihedral Mn-O-N-Mn (torsion) angle. A linear correlation is found, with the magnitude of J varying significantly as the dihedral angle is altered. As the torsion angle increases the AF exchange decreases, matching the experimentally determined data. DFT calculations reveal that the dyzπ*dyz interaction decreases as the dihedral angle increases leading to ferromagnetic coupling at larger angles.

Synthesis of 1,2-benzisoxazole 2-oxides

(Chemical Equation Presented) A series of 2-hydroxyaryl ketoximes were converted to the corresponding 1,2- benzisoxazole 2-oxides by treatment with iodobenzene diacetate (in acetic acid or methanol) or N-chlorosuccinimide in water. Both methods gave moderate to excellent yields for a variety of substituted oximes under mild conditions within short reaction times. The latter method has the advantages of an aqueous solvent and lack of halogenated organic by-products. Copyright Taylor & Francis Group, LLC.

EPR and electronic spectral studies on copper(II) complexes of some N-O donor ligands

Complexes, [Cu(ligand-H)2] of copper(II) with hidentate nitrogen-oxygen donor ligands, viz. 2-hydroxynaphthaldehydeoxime[hnoH 2], 2-hydroxyacetophenoneoxime [haOH2], salicyladoxime [salH2] and 2-hydroxypropiophenoneoxime [hmpH2] hate been prepared. The complexes have square-planar geometry. The effect of axial ligand has also been studied by EPR spectra of the pyridine adduct of these complexes. Spectral features for diadducts are different compared to the monoadducts. All these pyridine adducts have tetragonal geometry.

1,2-Benzisoxazole Phosphorodiamidates as Novel Anticancer Prodrugs Requiring Bioreductive Activation

Several 1,2-benzisoxazole phosphorodiamidates have been designed as prodrugs of phosphoramide mustard requiring bioreductive activation. Enzymatic reduction of 1,2-benziosoxazole moiety is expected to result in the formation of imine intermediate due to t

Moessbauer and electronic spectral studies of iron(III) complexes of oximes.

The hydroxo-bridge complexes of the type [Fe(2)(ligand-H)(4)(OH)(2)] with bidentate nitrogen-oxygen donor ligands, viz. 2-hydroxynaphthaldehydeoxime [hnoH(2)], 2-hydroxyacetphenoneoxime [haoH(2)], salicylaldooxime [SalH(2)], 2-hydroxypropiophenoneoxime [hnoH(2)] have been prepared. All the complexes have been characterized by elemental analysis, magnetic moments, electronic and Moessbauer spectral studies. Moessbauer parameters of the complexes clearly suggest high spin configuration of Fe(III) showing lower magnetic moment to that of the spin only value, i.e. 5.92 BM. It may be due to the antiferromagnetic interaction between Fe(III) centers.