182683-91-6

Basic information

• Product Name: (2-methoxyphenyl)dimethylsilane
• Synonyms: (2-methoxyphenyl)dimethylsilane
• CAS NO: 182683-91-6
• Molecular Weight: 166.295
• Mol File: 182683-91-6.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: (2-methoxyphenyl)dimethylsilane(CAS DataBase Reference)
• NIST Chemistry Reference: (2-methoxyphenyl)dimethylsilane(182683-91-6)
• EPA Substance Registry System: (2-methoxyphenyl)dimethylsilane(182683-91-6)

Safety Data

• Hazardous Substances Data: 182683-91-6(Hazardous Substances Data)

Upstream product

• 1066-35-9 dimethylmonochlorosilane 
• 578-57-4 2-bromoanisole 
• 529-28-2 4-iodoanisol 
• 31600-86-9 2-methoxyphenyllithium 
• 332343-84-7 1,2-bis(2-methoxyphenyl)-1,1,2,2-tetramethyldisilane 
• 372200-20-9 (2-methoxyphenyl)dimethylsilyl lithium 
• 16750-63-3 2-methoxyphenylmagnesium bromide 

Downstream Products

• 60458-00-6 chloro(2-methoxyphenyl)dimethylsilane 
• 253185-03-4 tert-butylbenzene 
• 538-93-2 1-phenyl-2-methylpropane 

Relevant articles and documents

Selective Electrochemical Hydrolysis of Hydrosilanes to Silanols via Anodically Generated Silyl Cations

The first electrochemical hydrolysis of hydrosilanes to silanols under mild and neutral reaction conditions is reported. The practical protocol employs commercially available and cheap NHPI as a hydrogen-atom transfer (HAT) mediator and operates at room temperature with high selectivity, leading to various valuable silanols in moderate to good yields. Notably, this electrochemical method exhibits a broad substrate scope and high functional-group compatibility, and it is applicable to late-stage functionalization of complex molecules. Preliminary mechanistic studies suggest that the reaction appears to proceed through a nucleophilic substitution reaction of an electrogenerated silyl cation with H2O.

Ru(ii)-Pheox-catalyzed Si-H insertion reaction: construction of enantioenriched carbon and silicon centers

We established a highly enantioselective Si-H insertion reaction to construct chiral centers at the carbon and silicon atoms, using a Ru(ii)-pheox catalyst. The catalytic asymmetric Si-H insertion reaction of α-methyl-α-diazoesters proceeded smoothly with excellent stereoinduction at both the neighboring carbon and silicon atoms (up to 99% yield and 99% ee).

Rhodium-catalyzed carbonylative synthesis of silyl-substituted indenones

A novel and efficient rhodium-catalyzed procedure for the preparation of silyl-substituted indenones has been developed. Using silanes and internal alkynes as the substrates, in the presence of CO, good to excellent yields of the desired indenones were isolated. A wide range of functional groups, encompassing esters, amines, nitriles and halides, is compatible in this system.