182699-53-2Relevant academic research and scientific papers
Reactivity of conjugated azoalkenes towards α-amino acid ethyl esters
Bozzini, Silvano,Felluga, Fulvia,Nardin, Giorgio,Pizzioli, Alessandro,Pitacco, Giuliana,Valentin, Ennio
, p. 1961 - 1969 (1996)
The synthesis of Z- and E-arylhydrazones by 1,4-conjugate addition of glycine, L-alanine and L-tyrosine ethyl esters to phenylazostilbene 1,p-nitrophenylazostilbene 2 and p-nitrophenylazocyclohexene 3 is described. Optically active N-functionalized 2-aminocyclohexanones 22-26 are obtained by TiCl3-catalysed hydrolysis of the corresponding hydrazones. However, they have been shown to be unstable, as they undergo easy oxidation by air. X-Ray analysis of the phenylhydrazone 8a in the Z configuration is also reported.
