182865-75-4

Upstream product

• 182865-72-1 Acetic acid (2R,3R,4S,5S,6R)-4,5-diacetoxy-6-acetoxymethyl-2-((2R,4aR,6R,7R,8R,8aS)-7-allyloxycarbonylamino-6-ethoxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-8-yloxy)-tetrahydro-pyran-3-yl ester 
• 182865-97-0 Ethyl 3,4,6tri-O-acetyl-2-deoxy-2-allyloxycarbonylamino-β-D-gluco-pyranoside 
• 182865-71-0 ((2R,4aR,6R,7R,8R,8aS)-6-Ethoxy-8-hydroxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-7-yl)-carbamic acid allyl ester 
• 182865-98-1 ((2R,3R,4R,5S,6R)-2-Ethoxy-4,5-dihydroxy-6-hydroxymethyl-tetrahydro-pyran-3-yl)-carbamic acid allyl ester 
• 112929-24-5 1,3,4,6-tetra-O-acetyl-2-deoxy-2-(allyloxycarbonylamino)-β-D-glucopyranose 
• 128571-86-8 2,3,4-tri-O-acetyl-α-L-fucopyranosyl trichloroacetimidate 
• 182865-74-3 Acetic acid (2R,3R,4S,5S,6R)-4,5-diacetoxy-6-acetoxymethyl-2-((2R,3R,4R,5S,6R)-3-allyloxycarbonylamino-6-benzyloxymethyl-2-ethoxy-5-hydroxy-tetrahydro-pyran-4-yloxy)-tetrahydro-pyran-3-yl ester 

Downstream Products

• 182865-76-5 Acetic acid (2R,3S,4R,5R,6S)-4,5-diacetoxy-2-[(2R,3S,4R,5R,6R)-5-amino-2-benzyloxymethyl-6-ethoxy-4-((2R,3R,4S,5S,6R)-3,4,5-triacetoxy-6-acetoxymethyl-tetrahydro-pyran-2-yloxy)-tetrahydro-pyran-3-yloxy]-6-methyl-tetrahydro-pyran-3-yl ester 
• 182865-77-6 Acetic acid (2R,3R,4S,5S,6R)-4,5-diacetoxy-6-acetoxymethyl-2-[(2R,3R,4R,5S,6R)-3-acetylamino-6-benzyloxymethyl-2-ethoxy-5-((2R,3S,4R,5R,6S)-3,4,5-triacetoxy-6-methyl-tetrahydro-pyran-2-yloxy)-tetrahydro-pyran-4-yloxy]-tetrahydro-pyran-3-yl ester 

Relevant academic research and scientific papers

Stereoselective synthesis of Lewis-associated trisaccharides as E-selectin inhibitors

Three types of Lewis-associated trisaccharides [the Lea analogs, their epimers with respect to the fucose residue (the 1c-epi-Lea analogs), and the Le(x) analogs] were synthesized in a stereoselective manner. Not only the Lea analogs but also the 1c-epi-Lea analogs inhibited E-selectin-mediated neutrophil accumulation into pleural cavity in lipoteichoic acid-treated mice, with the trend being Lea > 1c-epi-Lea > Le(x).