182875-05-4

Basic information

• Product Name: Benzoic acid, 2,4,5-trifluoro-, 1,1-dimethylethyl ester
• Synonyms: Benzoic acid,2,4,5-trifluoro-,1,1-dimethylethyl ester
• CAS NO: 182875-05-4
• Molecular Formula: C11H11F3O2
• Molecular Weight: 232.202
• Mol File: 182875-05-4.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 2,4,5-trifluoro-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 2,4,5-trifluoro-, 1,1-dimethylethyl ester(182875-05-4)
• EPA Substance Registry System: Benzoic acid, 2,4,5-trifluoro-, 1,1-dimethylethyl ester(182875-05-4)

Safety Data

• Hazardous Substances Data: 182875-05-4(Hazardous Substances Data)

Upstream product

• 88419-56-1 2,4,5-trifluorobenzoyl chloride 
• 75-65-0 tert-butyl alcohol 
• 24424-99-5 di-tert-butyl dicarbonate 
• 446-17-3 2,4,5-trifluorobenzoic acid 

Downstream Products

• 182874-95-9 tert-butyl 4-(benzyloxy)-2,5-difluorobenzoate 
• 1010800-83-5 t-butyl 2,5-difluoro-4-methoxybenzoate 
• 1446444-68-3 tert-butyl 4-((5-chloro-6-isopropoxypyridin-3-yl)oxy)-2,5-difluorobenzoate 
• 1443431-08-0 4-[(5-chloro-6-isopropoxypyridin-3-yl)methoxy]-N-[(dimethylamino)sulfonyl]-2,5-difluorobenzamide 
• 1355066-47-5 tert-butyl 4-{[5-chloro-6-(tetrahydro-2H-pyran-4-yloxy)pyridin-3-yl]oxy}-2,5-difluorobenzoate 
• 1355066-46-4 4-{[5-Chloro-6-(tetrahydro-2H-pyran-4-yloxy)pyridin-3-yl]oxy}-2,5-difluorobenzoic acid 
• 1355063-61-4 4-(5-chloro-6-methoxypyridin-3-yloxy)-N-(cyclopropylsulfonyl)-2,5-difluorobenzamide diethylamine salt 
• 1355066-43-1 lithium salt of 4-(5-chloro-6-methoxypyridin-3-yloxy)-2,5-difluorobenzoic acid 
• 1355063-48-7 4-({5-Chloro-6-[(3,3-difluorocyclobutyl)methoxy]pyridin-3-yl}oxy)-2,5-difluoro-N-(methylsulfonyl)benzamide 
• 1355066-38-4 tert-Butyl 4-({5-chloro-6-[(3,3-difluorocyclobutyl)methoxy]pyridin-3-yl}oxy)-2,5-difluorobenzoate 
• 1355066-44-2 tert-butyl 4-(5-chloro-6-methoxypyridin-3-yloxy)-2,5-difluorobenzoate 
• 1355066-39-5 4-({5-Chloro-6-[(3,3-difluorocyclobutyl)methoxy]pyridin-3-yl}oxy)-2,5-difluorobenzoic acid 

Relevant articles and documents

Introducing efficient palladium catalyzed cross coupling reaction of tertiary alcohols and aroyl chlorides for the synthesis of highly substituted esters

Esters are chemical compounds with many practical uses. The common type of esterification is called the Fischer esterification. Another one is by the action of acid chlorides on alcohols but not with tertiary alcohols. The stable carbenium ions formed fro

2,4,5-TRISUBSTITUTED 1,2,4-TRIAZOLONES USEFUL AS INHIBITORS OF DHODH

The present invention provides triazolone compounds compounds of general formula (I) : in which R1, R2, R3, R4 and R5 are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of hyperproliferative disorders, as a sole agent or in combination with other active ingredients.

CHEMICAL COMPOUNDS

The invention relates to sulfonamide derivatives, to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes. More particularly the invention relates to a new sulfonamide Nav1.7 inhibitors of formula (I): or a pharmaceutically acceptable salt thereof, wherein Het1, X, R1, R2, R3, R4 and R5 are as defined in the description. Nav 1.7 inhibitors are potentially useful in the treatment of a wide range of disorders, particularly pain