182876-90-0Relevant academic research and scientific papers
Ring-based analogues of pentamidine versus P. carinii pneumonia in culture
Delia, Thomas J.,Nagarajan,Queener, Sherry F.,Bartlet, Marilyn S.
, p. 2367 - 2370 (1996)
The synthesis of aromatic ring-based pentamidine analogues, in which the aliphatic bridge has been replaced by benzene, pyridine, or pyrimidine has been accomplished in two steps. Compounds containing benzene and pyridine as the central core of the molecule have demonstrated activity against PCP in culture.
Benzamidine derivatives and their use as anti-coagulants
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Page column 34, (2010/02/04)
This invention is directed to benzamidine derivatives which are useful as anti-coagulants. This invention is also directed to pharmaceutical compositions containing the compounds of the invention, and methods of using the compounds to treat disease-states characterized by thrombotic activity.
