182879-70-5Relevant academic research and scientific papers
Copper-Promoted N-Arylation of the Imidazole Side Chain of Protected Histidine by Using Triarylbismuth Reagents
Chan, Hwai-Chien,Bueno, Bianca,Le Roch, Adrien,Gagnon, Alexandre
supporting information, p. 13330 - 13336 (2021/08/09)
The N-arylation of the side chain of histidine by using triarylbismuthines is reported. The reaction is promoted by copper(II) acetate in dichloromethane at 40 °C under oxygen in the presence of diisopropylethylamine and 1,10-phenanthroline and allows the transfer of aryl groups with substituents at any position of the aromatic ring. The reaction shows excellent functional group tolerance and is applicable to dipeptides where the histidine is located at the N terminus. A histidine-guided backbone N?H arylation was observed in dipeptides where the histidine occupies the C terminus.
Design, synthesis, and complementary recognition of β-hairpin peptides stabilized by artificial DNA base-pairing amino acids
Isozaki, Katsuhiro,Miki, Kazushi
supporting information; experimental part, p. 2947 - 2949 (2010/08/04)
A novel DNA base-pairing β-hairpin peptide involving intramolecular hydrogen bonds for induction of β-hairpin secondary structure and intermolecular complementary hydrogen bonds between thymine and diaminopyridine for molecular recognition has been synthe
