80870-38-8

Upstream product

• 4818-08-0 N-Z-L-phenylalanyl-L-valine methylester 
• 2754-02-1 N-(N-(1,1-dimethylethoxycarbonyl)-L-phenylalanyl)-L-valine methyl ester 
• 6306-52-1 L-valine methylester hydrochloride 
• 103321-57-9 2S-flouren-9-ylmethoxycarbonylamino-3-phenylpropionyl chloride 
• 4070-48-8 L-Valine methyl ester 
• 63-91-2 L-phenylalanine 
• 75-24-1 trimethylaluminum 
• 13734-34-4 N-tert-butoxycarbonyl-L-phenylalanine 
• 2462-34-2 L-valine benzyl ester hydrochloride 
• 98131-22-7 Pht
• 827018-98-4 Fmoc-Phe-Val-OMe 

Downstream Products

• 84255-90-3 Ac-ΔPhe-Phe-Val-OMe 
• 120418-41-9 CBZPhePheValOCH₃ 
• 849925-49-1 Boc-Leu-Phe-Val-OMe 
• 53842-46-9 Ac-Phe-Val-OMe 
• 182879-70-5 Boc-Ala-Phe-Val-OMe 
• 119621-70-4 C₂₆H₄₀N₄O₅ 
• 1384313-98-7 Boc-Leu-Phe-Val-^DPro-Aib-Leu-Phe-Val-OMe 

Relevant academic research and scientific papers

Synthesis and biological evaluation of a novel series of curcumin-peptide derivatives as PepT1-mediated transport drugs

Curcumin (CUR) is a natural yellow pigment from turmeric with extensive bioactivities. However its relatively poor solubility limited its absorption and bioavailability. In this study, a novel series of CUR-peptide conjugates were designed and synthesized

Site-selective C(sp3)-H functionalization of di-, tri-, and tetrapeptides at the N-terminus

Although the syntheses of novel and diverse peptides rely mainly on traditional coupling using unnatural amino acids, postsynthetic modification of peptides could provide a complementary method for the preparation of nonproteinogenic peptides. Site select

Analysis of designed β-hairpin peptides: Molecular conformation and packing in crystals

The crystal structures of several designed peptide hairpins have been determined in order to establish features of molecular conformations and modes of aggregation in the crystals. Hairpin formation has been induced using a centrally positioned D/su

Application of rapidly generated bidentate ligand libraries to zinc catalyzed reductions

A methodology for the combinatorial synthesis of bidentate ligands - allowing direct screening of reaction products without the need for isolation or purification - has been employed in a zinc catalyzed hydrosilylation. This reaction allowed the robustness of the methodology to be examined, by employing it in a challenging case where the metal complex is not pre-formed prior to catalysis. Four different ligand families have been examined: imines, aminals, bis-imines and oxazolines and related compounds, with a small library of each type produced and directly screened in the reaction. Three ligands providing enantioselectivities of 50% or more in this very challenging reaction were identified, and ees and conversions were equivalent whether the ligand was obtained as a crude mixture from a library synthesis or as an isolated, purified compound.

Design, synthesis, and complementary recognition of β-hairpin peptides stabilized by artificial DNA base-pairing amino acids

A novel DNA base-pairing β-hairpin peptide involving intramolecular hydrogen bonds for induction of β-hairpin secondary structure and intermolecular complementary hydrogen bonds between thymine and diaminopyridine for molecular recognition has been synthe

Expanding the peptide β -turn in α γ hybrid sequences: 12 atom hydrogen bonded helical and hairpin turns

Hybrid peptide segments containing contiguous a and y amino acid residues can form C 12 hydrogen bonded turns which may be consideredas backbone expanded analogues of C 10 OS-turns) found in aa segments. Exploration of the regular hy

Alternative and chemoselective deprotection of the α-amino and carboxy functions of N-Fmoc-amino acid and N-Fmoc-dipeptide methyl esters by modulation of the molar ratio in the AlCl3/N,N-dimethylaniline reagent system

The amino and carboxy functions in N-Fmoc-α-amino acid and N-Fmoc-peptide methyl esters can be alternatively and chemoselectively deprotected by treatment with the reagent system AlCl3/N,N- dimethylaniline (DMA). The chemoselectivity of the process is controlled by modulating the relative molar ratio of the Lewis acid and DMA. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004.

Differences arising in human neutrophil activation passing from N-formyl to N-acetyl-oligopeptides

N-formyl- and N-acetyl-peptides were synthesized and compared in order to understand which features can best elicit biological responses. The behavior of N-formyl-peptides confirms the previously found sequential obligations in the residues, while acetyl-

Herbicidal imidazolones

Compounds such as Formula I having herbicidal utility are disclosed: STR1 wherein Q is STR2 R1 is H; alkyl, haloalkyl or halogen R2 is C1 -C2 alkyl optionally substituted with one or more halogens, OR8, CN, COR9, CO2 R31 or CONR32 R33 ; CN; CO2 R34 ; CONR35 R36 ; S(O)n R8 ; S(O)n NR19 R8 or COR37 ; or R1 and R2 can be taken together along with the carbon to which they are attached to form C=CHCO2 R31 ; C=(CH3)CO2 R31 ; C=(C2 H5)CO2 R31 ; C=CHCONR32 R33 ; C=C(CH3)CONR32 R33 or C=C(C2 H5)CONR32 R33.