182934-49-2Relevant academic research and scientific papers
Synthesis and nucleic-acid-binding properties of sulfamide- and 3′-N-sulfamate-modified DNA
Fettes, Kevin J.,Howard, Nigel,Hickman, David T.,Adah, Steven,Player, Mark R.,Torrence, Paul F.,Micklefield, Jason
, p. 485 - 495 (2002)
A novel synthetic route for the preparation of sulfamide- and 3′-N-sulfamate-modified dinucleosides has been developed. The synthesis utilises 4-nitrophenyl chlorosulfate to prepare 4-nitrophenyl 3′- or 5′-sulfamates (e.g.,18 and 27), which couple smoothl
