182949-17-3

Upstream product

• 124-63-0 methanesulfonyl chloride 
• 182949-16-2 (3R,4R)-6-Benzyloxy-4-methylhexane-1,3-diol 
• 144781-81-7 methyl (3S,4R)-4-(tert-butyldimethylsiloxy)-3,7-dimethyl-6-octenoate 
• 144781-72-6 (1R,2R,3R,5R)-3-(tert-Butyl-dimethyl-silanyloxy)-5-(1-chloro-1-methyl-ethyl)-2-methyl-cyclopentanecarboxylic acid methyl ester 
• 182949-14-0 [(R)-1-((R)-3-Benzyloxy-1-methyl-propyl)-4-methyl-pent-3-enyloxy]-tert-butyl-dimethyl-silane 
• 182949-15-1 (3R,4R)-6-Benzyloxy-3-(tert-butyl-dimethyl-silanyloxy)-4-methyl-hexanal 
• 182949-13-9 (3R,4R)-4-(tert-Butyl-dimethyl-silanyloxy)-3,7-dimethyl-oct-6-en-1-ol 

Downstream Products

• 67314-15-2 (24R,25R,26R)-petrosterol 
• 182949-23-1 (1R,2R)-2-((1R)-3-Benzyloxy-1-methylpropyl)-1-methylcyclopropane 
• 182949-22-0 [(1R,2S)-2-((R)-3-Benzyloxy-1-methyl-propyl)-cyclopropyl]-methanol 
• 182949-21-9 (1R,2S)-2-((1R)-3-Benzyloxy-1-methylpropyl)cyclopropane-1-carbaldehyde 
• 182949-20-8 (1R,2S)-2-((1R)-3-Benzyloxy-1-methylpropyl)cyclopropane-1-carbonitrile 
• 1027248-91-4 Methanesulfonic acid (1R,2S)-2-((R)-3-benzyloxy-1-methyl-propyl)-cyclopropylmethyl ester 
• 182949-19-5 Methanesulfonic acid (1R,2R)-4-benzyloxy-1-(2-cyano-ethyl)-2-methyl-butyl ester 
• 182949-18-4 (4R,5R)-7-Benzyloxy-4-hydroxy-5-methyl-heptanenitrile 

Relevant academic research and scientific papers

Stereoselective synthesis of petrosterol and a formal synthesis of aragusterols

Stereoselective construction of a steroidal side chain containing a 26-27 cyclopropane ring, compound 22, has been achieved by an intramolecular cyclisation of the corresponding β-methylsulfonyloxy cyanide 16, derived from a chiral cyclopentane derivative. Compound 22 has been further utilised in the synthesis of the naturally occurring steroid petrosterol 3.