182955-10-8 Usage
Molecular Structure
Complex, containing a pyrimidine ring with methyl and phenylcarbonyl substituents
Medicinal Uses
Treatment of leprosy, multiple myeloma, and certain inflammatory diseases
Sedative and Hypnotic Properties
Used as a sleep aid in the past
Birth Defects Association
Known to cause severe birth defects when taken during pregnancy
Market Withdrawal
Withdrawn from the market in the 1960s due to teratogenic effects
Resurgence in Medical Use
Recent years have seen a resurgence in its use due to potential effectiveness in treating various conditions
Strictly Controlled Use
Use is carefully monitored and controlled due to its teratogenic effects
Molecular Weight
Approximately 244.25 g/mol
Appearance
White to off-white crystalline solid
Solubility
Soluble in organic solvents like dimethyl sulfoxide (DMSO) and slightly soluble in water
Melting Point
Around 263-266°C
Check Digit Verification of cas no
The CAS Registry Mumber 182955-10-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,2,9,5 and 5 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 182955-10:
(8*1)+(7*8)+(6*2)+(5*9)+(4*5)+(3*5)+(2*1)+(1*0)=158
158 % 10 = 8
So 182955-10-8 is a valid CAS Registry Number.
182955-10-8Relevant articles and documents
COMPOSITIONS, METHODS OF USE, AND METHODS OF TREATMENT
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Page/Page column 37; 38, (2015/04/15)
Embodiments of the present disclosure provide for compositions including an antimicrobial agent, pharmaceutical compositions including the antimicrobial agent, methods of treatment of an infection, methods of treatment using compositions or pharmaceutical
Simple, Efficient, High Yield Syntheses of Substituted and Unsubstituted 5-Benzoylbarbituric Acids, and Their Corresponding Schiff Base Phenylhydrazones
Jursic, Branko S.,Neumann, Donna M.,Bowdy, Katharine L.,Stevens, Edwin D.
, p. 233 - 246 (2007/10/03)
Preparation procedures for biologically important benzoylbarbiturates are presented. Several procedures are optimized to cover the preparations of a wide variety of substituted 5-benzoylbarbiturates. To further explore the biological importance of these c
