182962-07-8

Upstream product

• 4762-26-9 hexyltriphenylphosphonium bromide 
• 182962-05-6 (4S,5S)-5-benzyloxymethyl-3-N-tert-butoxycarbonyl-4-formyl-2,2-dimethyl-1,3-oxazolidine 
• 182962-01-2 (4R,5S)-5-Benzyloxymethyl-4-(tert-butyl-diphenyl-silanyloxymethyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 182962-03-4 (4R,5S)-5-benzyloxymethyl-3-N-tert-butoxycarbonyl-4-hydroxymethyl-2,2-dimethyl-1,3-oxazolidine 
• 176967-05-8 (4R,5S)-4-(tert-Butyl-diphenyl-silanyloxymethyl)-5-hydroxymethyl-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 100-39-0 benzyl bromide 

Relevant academic research and scientific papers

Synthesis of (2S,3R)-3-amino-2-hydroxydecanoic acid and (3R,4R)-3-amino-4-hydroxyazepane from D-isoascorbic acid

Taking advantage of the high functionally of an enantiopure protected syn-2R-amino-1,3,4-triol derivative, easily available on a multigram scale from D-isoascorbic acid, several biologically active compounds have been synthesized such as the (2S,3R)-3-amino-2-hydroxydecanoic acid (AHDA), the N-terminal moiety of microginin, and the (3R,4R)-3-amino-4-hydroxyazepane, the ophiocordin and balanol core structure.