1830-32-6 Usage
Originator
Azintamide,Bristhar
Laboratorios
Manufacturing Process
7.3 parts of 3-chloro-6-mercaptopyridazine are neutralised with 20 parts of
10% caustic soda solution, diluted with 60 parts of 50% ethanol, and heated
to 60°C. 7.5 parts of chloroacetic acid diethyl amide dissolved in 20 parts of
ethanol are added to this solution over a period of 10 min and the resulting
mixture is heated to 60°C for 30 min. The reaction solution is then cooled, the resulting crystallisate is removed by suction, and the filtrate is extracted with
ethyl acetate. The solvent is removed by evaporation and the concentration
residue is combined with the crystallisate. After two recrystallisations from
benzene, 11 parts of 3-chloro-pyridazine-6-mercaptoacetic acid diethyl amide,
having a melting point of from 139° to 140°C are yielded.
Therapeutic Function
Choleretic
Check Digit Verification of cas no
The CAS Registry Mumber 1830-32-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,8,3 and 0 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1830-32:
(6*1)+(5*8)+(4*3)+(3*0)+(2*3)+(1*2)=66
66 % 10 = 6
So 1830-32-6 is a valid CAS Registry Number.
InChI:InChI=1/C10H14ClN3OS/c1-3-14(4-2)10(15)7-16-9-6-5-8(11)12-13-9/h5-6H,3-4,7H2,1-2H3
1830-32-6Relevant articles and documents
Method for preparing azinamide
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Paragraph 0043; 0044; 0049; 0050; 0055; 0056, (2018/07/30)
The invention discloses a method for preparing azinamide. The method comprises preparing an azinamide thiol compound solution, preparing the azinamide by reaction, and then purifying the azinamide. The method is characterized in that in the process of preparing of the azinamide thiol compound solution, water and sodium sulfide are mixed and dissolved; sulfur is added and dissolved; a 3,6-dichloropyridazine reaction system is added in batches, sodium sulfite is added to prevent oxidation; in the process of preparing of the azinamide, first the sodium sulfite is added to prevent oxidation, thena liquid mixture of ethanol and N,N-diethyl-2-chloroacetamide is added dropwise, meanwhile pH is monitored within the range of 8-10; and the azinamide is purified. The method for preparing the azinamide has the advantages of being simple in steps, green, environmentally-friendly, high in yield, low in processing cost, and suitable for mass production.
