18304-61-5

Upstream product

• 19883-13-7 DL-threo-N-acetyl-3-hydroxy-glutamic acid diethyl ester 
• 7683-74-1 DL-erythro-3-hydroxy-glutamic acid diethyl ester; hydrochloride 
• 97315-78-1 diethyl α-aminoacetonedicarboxylate 
• 102076-70-0 DL-erythro-N-benzoyl-3-hydroxy-glutamic acid diethyl ester 
• 97336-09-9 diethyl 2-acetamido-3-ketoglutarate 
• 996-75-8 diethyl 2-nitroso-3-ketoglutarate 
• 7683-73-0 diethyl 3-hydroxyglutamate 
• 19883-13-7 diethyl N-acetyl-3-hydroxyglutamate 
• 105-50-0 diethyl 1,3-acetonedicarboxylate 
• 7705-08-0 iron(III) chloride 

Downstream Products

• 328-50-7 α-ketoglutaric acid 
• 7664-41-7 ammonia 
• 107-43-7 betaine 

Relevant academic research and scientific papers

Kutznerides 1-4, depsipeptides from the actinomycete Kutzneria sp. 744 inhabiting mycorrhizal roots of Picea abies seedlings

Bioassay-guided fractionation of culture supernatants of the actinomycete Kutzneria sp. 744 resulted in the isolation of four new depsipeptides (1-4). Structure analysis revealed the general structure: cyclo[2-(1-methylcyclopropyl) -D-glycine-(2S,3aR,8aS)

L-threo- and L-erythro-3-Fluoroglutamic Acids. Synthesis by Fluorodehydroxylation and Enzymatic Resolution.

threo- and erythro-3-fluoroglutamic acids were prepared by fluorodehydroxylation of N-acetyl-3-hydroxyglutamic acids according to Kollonitsch.Following ion exchange column separation of the diastereoisomers, enzymatic deacylation by acylase I afforded optically pure L-isomers of the 3-fluoroglutamic acid.Assignment of structure was achieved by correlation with cis- and trans-3-fluoropyroglutamic acids.The results indicate predominant inversion of configuration during the fluorodehydroxylation reaction.