183064-96-2Relevant academic research and scientific papers
Synthesis of β,γ-unsaturated N-acyl-2-oxazolidinones
Dobarro, Alicia,Velasco, Dolores
, p. 13525 - 13530 (1996)
An effective imide formation method is presented, which allows the preparation of β,γ-unsaturated N-acyl-2-oxazolidinones with high yields and without isomerization of the double bond to give the α,γ-unsaturated isomers, which are the inevitable by-products when alternative procedures are used.
Synthesis of β,γ-unsaturated N-acyl-2-oxazolidinones
Dobarro, Alicia,Velasco, Dolores
, p. 13733 - 13738 (1996)
An effective imide formation method is presented, which allows the preparation of β,γ-unsaturated N-acyl-2-oxazolidinones with high yields and without isomerization of the double bond to give the α,β-unsaturated isomers, which are the inevitable by-products when alternative procedures are used.
FURO [3, 2-B] PYRR0L-3-0NES AS CATHEPSIN S INHIBITORS
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Page/Page column 86, (2009/10/22)
A first aspect of the invention relates to a compound of formula (I), or a pharmaceutically acceptable salt, hydrate, complex or pro-drug thereof, wherein: one of R3 and R4 is H, and the other is selected from C1-6-alkyl,
The 'SuperQuat' (R)-4-phenyl-5,5-dimethyl oxazolidin-2-one as an effective chiral auxiliary for conjugate additions: Asymmetric synthesis of (-)-aplysillamide B.
Davies, Stephen G.,Sanganee, Hitesh J.,Szolcsanyi, Peter
, p. 3337 - 3354 (2007/10/03)
(R)-4-Phenyl-5,5-dimethyl-oxazolidin-2-one, readily available from D- phenylglycine, is shown to be an effective chiral auxiliary for stereoselective conjugate additions to attached α,β-unsaturated N-acyl moieties. Its utility is demonstrated by the asymmetric synthesis of the antifungal, antibacterial (-)-Aplysillamide B.
