183127-70-0

Basic information

• Product Name: (RS)-3-Diphenylphosphinoyl-2-phenylpropane-1,2-diol
• Synonyms: (RS)-3-Diphenylphosphinoyl-2-phenylpropane-1,2-diol
• CAS NO: 183127-70-0
• Molecular Weight: 352.37
• Mol File: 183127-70-0.mol

Chemical Properties

• CAS DataBase Reference: (RS)-3-Diphenylphosphinoyl-2-phenylpropane-1,2-diol(CAS DataBase Reference)
• NIST Chemistry Reference: (RS)-3-Diphenylphosphinoyl-2-phenylpropane-1,2-diol(183127-70-0)
• EPA Substance Registry System: (RS)-3-Diphenylphosphinoyl-2-phenylpropane-1,2-diol(183127-70-0)

Safety Data

• Hazardous Substances Data: 183127-70-0(Hazardous Substances Data)

Upstream product

• 1079-66-9 chloro-diphenylphosphine 
• 98-81-7 1-bromovinylbenzene 
• 42104-30-3 3-diphenylphosphinoyl-2-phenylprop-1-ene 

Downstream Products

• 165557-46-0 (R)-3-Diphenylphosphinoyl-2-hydroxy-2-phenylpropanal 
• 165557-47-1 (S)-3-Diphenylphosphinoyl-2-hydroxy-2-phenylpropanal 

Relevant articles and documents

An Efficient Protocol for a Sharpless Style Racemic Dihydroxylation

Dihydroxylation with solid OsCl3 to provide the catalytic oxidant, K3Fe(CN)6 as stoichiometric oxidant, quinuclidine as the accelerating ligand with added K2CO3 and methanesulfonamide in a two-phase system (water and t-butanol) gives excellent yields of r

An efficient protocol for Sharpless-style racemic dihydroxylation

Racemic dihydroxylation of alkenes is efficiently accomplished with catalytic osmium (added as OsCl3), stoichiometric K3Fe(CN)6 and quinuclidine under conditions similar to those of the Sharpless asymmetric hydroxylation.

Synthesis of (R)- or (S)-diphenylphosphinoyl hydroxy aldehydes and 1,2-diols using Mukaiyama's bicyclic aminal methodology and Sharpless asymmetric dihydroxylation

Two different approaches to diphenylphosphinoyl hydroxy aldehydes and 1,2-diols are compared. A lengthy chiral auxiliary approach using proline-derived aminals enables hydroxy aldehydes and 1,2-diols of known absolute stereochemistry and high enantiomeric