42104-30-3Relevant articles and documents
Copper-Catalyzed Decarboxylative Functionalization of Conjugated β, Γ-Unsaturated Carboxylic Acids
Zhang, Wei,Wang, Chengming,Wang, Qiu
, p. 13179 - 13185 (2020/11/17)
Copper-catalyzed decarboxylative coupling reactions of conjugated β,γ-unsaturated carboxylic acids have been achieved for allylic amination, alkylation, sulfonylation, and phosphinoylation. This approach was effective for a broad scope of amino, alkyl, su
Copper-catalyzed oxidative cross-coupling of H-phosphine oxides with alkenes in the synthesis of alkenylphosphine oxides
Mao, Liu-Liang,Zhou, An-Xi,Liu, Na,Yang, Shang-Dong
, p. 2727 - 2732 (2015/06/25)
Abstract The first copper-catalyzed alkene oxidative cross-coupling reaction with various R2P(O)H compounds has been reported, affording a novel and efficient method for the synthesis of valuable alkenylphosphine oxides compounds with broad sub
An efficient protocol for Sharpless-style racemic dihydroxylation
Eames, Jason,Mitchell, Helen J.,Nelson, Adam,O'Brien, Peter,Warren, Stuart,Wyatt, Paul
, p. 1095 - 1104 (2007/10/03)
Racemic dihydroxylation of alkenes is efficiently accomplished with catalytic osmium (added as OsCl3), stoichiometric K3Fe(CN)6 and quinuclidine under conditions similar to those of the Sharpless asymmetric hydroxylation.
Synthesis of (R)- or (S)-diphenylphosphinoyl hydroxy aldehydes and 1,2-diols using Mukaiyama's bicyclic aminal methodology and Sharpless asymmetric dihydroxylation
O'Brien, Peter,Warren, Stuart
, p. 2129 - 2138 (2007/10/03)
Two different approaches to diphenylphosphinoyl hydroxy aldehydes and 1,2-diols are compared. A lengthy chiral auxiliary approach using proline-derived aminals enables hydroxy aldehydes and 1,2-diols of known absolute stereochemistry and high enantiomeric
Asymmetric dihydroxylations of allylic phosphine oxides
Nelson,O'Brien,Warren
, p. 2685 - 2688 (2007/10/02)
Allylic phosphine oxides 6 undergo asymmetric dihydroxylation to yield 1,2 diols 9. The enantioselectivity of these reactions depends critically on the class and quantity of chiral ligand used. A model to explain the sense and degree of asymmetric inducti
Cerium chloride (III) promoteid nucleophilic addition of organolithium reagents to α-diphenylphosphinoyl ketones. An efficient-method for the synthesis of Horner-Wittig intermediates
Bartoli,Sambri,Marcantoni,Petrini
, p. 8453 - 8456 (2007/10/02)
Reaction of α-diphenylphosphinoyl ketones with organolithium reagents, in the presence or anhydrous CeCl3 in THF at -78°C, affords β-hydroxyalkylphosphine oxides in fair to good yields. These are essential to obtain olefins with β-carbon disubs
A Simple Preparation of Vinyl- or Allyldiphenylphosphine Oxides
Santelli-Rouvier, Christiane
, p. 64 - 66 (2007/10/02)
A general route to 2- or 2,2-substituted vinyldiphenylphosphine oxides or allyldiphenylphosphine oxides from ketones (or benzaldehyde) and the anion of methyldiphenylphosphine oxide is reported.The intially formed 2-hydroxyalkyldiphenylphosphine oxide is
