183155-14-8Relevant academic research and scientific papers
Iron(III) tosylate catalyzed acylation of alcohols, phenols, and aldehydes
Baldwin, Neil J.,Nord, Anna N.,O'Donnell, Brendan D.,Mohan, Ram S.
, p. 6946 - 6949 (2012)
Iron(III) p-toluenesulfonate (tosylate) is an efficient catalyst for acetylation of alcohols, phenols, and aldehydes. The acetylation of 1° and 2° alcohols, diols, and phenols proceeded smoothly with 2.0 mol % of catalyst. However, the reaction worked well with only a few 3° alcohols. The methodology was also applicable to the synthesis of a few benzoate esters but required the use of 5.0 mol % catalyst. Aldehydes could also be converted into the corresponding 1,1-diesters (acylals) under the reaction conditions. Iron(III) tosylate is an inexpensive, and easy to handle, commercially available catalyst.
