183155-28-4Relevant academic research and scientific papers
Catalytic Isohypsic-Redox Sequences for the Rapid Generation of Csp3-Containing Heterocycles
Smith, Craig D.,Phillips, David,Tirla, Alina,France, David J.
supporting information, p. 17201 - 17204 (2018/11/10)
Cross-coupling reactions catalyzed by transition metals are among the most influential in modern synthetic chemistry. The vast majority of transition-metal-catalyzed cross-couplings rely on a catalytic cycle involving alternating oxidation and reduction o
Expedited Synthesis of Matrine Analogues through an Oxidative Cascade Addition/Double-Cyclization Radical Process
Olguín-Uribe, Simón,Mijangos, Marco V.,Amador-Sánchez, Yoarhy A.,Sánchez-Carmona, Miguel A.,Miranda, Luis D.
supporting information, p. 2481 - 2485 (2017/05/12)
The addition of a nicotinate–xanthate derivative to N-allylindoles and N-allylpyrroles resulted in polycyclic heterocycle-fused pyridonaphthyridines through a tandem radical intermolecular/intramolecular oxidative addition reaction sequence that created three new C–C bonds and two new rings in a single event. Such polyheterocycles showcase the matrine alkaloid framework and are similar to indole–monoterpenoid natural products.
Synthesis of Substituted γ- and δ-Lactams via Pd-Catalyzed Alkene Carboamination Reactions
Boothe, Jordan R.,Shen, Yifan,Wolfe, John P.
, p. 2777 - 2786 (2017/03/14)
The synthesis of substituted γ- and δ-lactams via palladium-catalyzed alkene carboamination reactions between aryl halides and alkenes bearing pendant amides is described. The substrates for these reactions are generated in 1-3 steps from commercially ava
O-Iodoxybenzoic acid (IBX): A versatile reagent for the synthesis of N-substituted pyrroles mediated by β-cyclodextrin in water
Narayana Murthy,Nageswar
supporting information; experimental part, p. 4481 - 4484 (2011/09/19)
O-Iodoxybenzoic acid (IBX), a very mild and efficient hypervalent iodine(V) reagent, aromatizes diversely substituted 1-benzylpyrrolidines and N-substituted l-proline analogues to the corresponding substituted pyrroles in good to excellent yields under mild conditions mediated by β-cyclodextrin in water at room temperature. To the best of our knowledge, this is the first report on IBX, promoting complete aromatization leading to N-benzylpyrroles from the corresponding saturated five membered heterocyclic derivatives in water medium.
PYRROLE DERIVATIVE
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Page 88, (2010/02/06)
A novel pyrrole derivative represented by the following formula (1) and a salt thereof: wherein R1 means substituted alkenyl, etc.; R2 means substituted benzoyl, etc.; and R3 to R5 each means hydrogen, alkyl, halogeno, etc. The derivative and salt have antidiabetic activity.
Efficient and practical method for synthesizing N-heterocyclic compounds using intramolecular nucleophilic acyl substitution reactions mediated by Ti(O-i-Pr)4/2i-PrMgx reagent. Synthesis of quinolones, pyrroles, indoles, and optically active N-
Okamoto, Sentaro,Iwakubo, Masayuki,Kobayashi, Katsushige,Sato, Fumie
, p. 6984 - 6990 (2007/10/03)
Treatment of N-(2- or 3-alkynyl)amino esters with a low-valent titanium reagent diisopropoxy(η2-propene)titanium (1), generated in situ by the reaction of Ti(O-i-Pr)4 and 2i-PrMgCl, resulted in an intramolecular nucleophilic acyl sub
