152668-35-4

Basic information

• Product Name: L-Proline, 1-(2-propenyl)-, methyl ester (9CI)
• Synonyms: L-Proline, 1-(2-propenyl)-, methyl ester (9CI);L-Proline, 1-(2-propenyl)-, Methyl ester
• CAS NO: 152668-35-4
• Molecular Formula: C₉H₁₅NO₂
• Molecular Weight: 169.2209
• Product Categories: PYRROLE
• Mol File: 152668-35-4.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 205.3±33.0 °C(Predicted)
• Appearance: /
• Density: 1.015±0.06 g/cm3(Predicted)
• PKA: 7.71±0.40(Predicted)
• CAS DataBase Reference: L-Proline, 1-(2-propenyl)-, methyl ester (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: L-Proline, 1-(2-propenyl)-, methyl ester (9CI)(152668-35-4)
• EPA Substance Registry System: L-Proline, 1-(2-propenyl)-, methyl ester (9CI)(152668-35-4)

Safety Data

• Hazardous Substances Data: 152668-35-4(Hazardous Substances Data)

Upstream product

• 147-85-3 L-proline 
• 591-87-7 Allyl acetate 
• 2577-48-2 methyl (2S)-pyrrolidine carboxylate 
• 2133-40-6 L-proline methyl ester monohydrochloride 
• 106-95-6 allyl bromide 

Downstream Products

• 2577-48-2 methyl (2S)-pyrrolidine carboxylate 
• 183155-28-4 methyl 1-allyl-1H-pyrrole-2-carboxylate 
• 1026390-17-9 (R)-1-((S)-2-Benzyloxymethyl-pyrrolidin-1-yl)-2-[(6-bromo-benzo[1,3]dioxol-5-ylmethyl)-(2,2-diethoxy-ethyl)-amino]-pent-4-en-1-one 
• 1026152-96-4 [(R)-1-((S)-2-Benzyloxymethyl-pyrrolidine-1-carbonyl)-but-3-enyl]-(2,2-diethoxy-ethyl)-carbamic acid tert-butyl ester 
• 210347-80-1 (S)-1-allyl-2-(benzyloxymethyl)pyrrolidine 

Relevant articles and documents

Catalyst- and Base-Free Asymmetric Synthesis of Functionalized Prolines via One-Pot Cascade Reactions

A one pot, three-step cascade reaction to provide functionalized proline derivatives was developed. The Michael addition reaction of N-allylated proline and activated alkyne forms a zwitterionic intermediate that further undergoes cyclization and [2,3]-re

A transition metal-catalyzed enyne metathesis for the preparation of pyrrolizidine alkaloid core: Application towards the total synthesis of stemaphylline

In this paper, we disclose an efficient route for the synthesis of pyrrolizidine alkaloid core and its application towards the total synthesis of stemaphylline. The key pyrrolizidine core was achieved with Ru-carbene catalyzed ring closing enyne metathesis (RCEM). The effect of different types and amounts of Ru-carbene catalysts, solvents and temperature were systematically studied. The advantage of this method includes the construction of pyrrolizidine alkaloid core in a single operation.

Synthesis of chiral triazine coupling reagents based on esters of n-alkylproline and their application in the enantioselective incorporation of d or l amino acid residue directly from racemic substrate

Esters of N-methylproline and N-allylproline were prepared and used as component for synthesis of chiral triazine based coupling reagents. N-Triazinylammonium tetrafluoroborate obtained from methylester of L-N-methylproline, 2-chloro-4,6-dimethozxy-1,3,5-