183200-98-8

Upstream product

• 183200-95-5 [(1S,2R)-1-Benzyl-2-(tert-butyl-dimethyl-silanyloxy)-2-phenyl-ethyl]-isopropyl-amine 
• 1066-50-8 Ethylphosphonic dichloride 
• 183200-96-6 (1R),(2S)-1,3-diphenyl-2-(N-isopropylamino)-1-propanol 
• 120390-75-2 (R)-(+)-α-<(tert-butyldimethylsilyl)oxy>-benzeneacetonitrile 
• 1589-82-8 phenylmagnesium bromide 

Relevant academic research and scientific papers

Design of β-amino alcohols as chiral auxiliaries in the electrophilic amination of 1,3,2-oxazaphospholanes

Theoretical studies to predict the diastereoselectivity of the electrophilic amination of chiral 1,3,2-oxazaphospholanes led to the design of (1R), (2S)-1,3-diphenyl-2-(N-isopropylamino)-1-propanol 7 as a powerful chiral auxiliary. The experimental results are in good agreement with the calculations. An efficient synthesis of enantiomerically pure 7 is also reported.