183203-29-4Relevant academic research and scientific papers
Copper-Mediated Deacylative Coupling of Ynones via C-C Bond Activation under Mild Conditions
Feng, Lili,Hu, Tingjun,Zhang, Saisai,Xiong, Heng-Ying,Zhang, Guangwu
supporting information, p. 9487 - 9492 (2019/12/02)
The intermolecular deacylative coupling of unstrained ynones via C-C bond activation was accomplished by a CuCl-bpy system under mild reaction conditions. This protocol features facile cleavage of the C-C bond at room temperature, broad substrate scope, and efficient construction of important symmetric and unsymmetrical 1,3-diyne adducts through homo or cross coupling of ynones, respectively. The preliminary mechanistic investigations indicated that an acyl copper(III) complex is likely involved in this process.
The reaction of carboxylic acid esters with RfMgBr: A convenient synthesis of perfluoroalkyl ketones
Xue, Can,He, Guangke,Fu, Chunling,Xue, Liqin,Lin, Zhenyang,Ma, Shengming
experimental part, p. 7012 - 7019 (2011/02/26)
An efficient method for the preparation of the synthetically attractive perfluoroalkyl ketones through the reaction of readily available alkenoates, alkynoates, or regular carboxylic esters with perfluoroalkyl Grignard reagents at -70 to -60 °C in diethyl
