183208-38-0

Basic information

• Product Name: 1H-Pyrrolo[2,3-b]pyridine-3-carboxaldehyde, 5-methoxy-
• Synonyms: 1H-Pyrrolo[2,3-b]pyridine-3-carboxaldehyde, 5-methoxy-;5-Methoxy-7-azaindole-3-carbaldehyde;5-Methoxy-1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde
• CAS NO: 183208-38-0
• Molecular Formula: C9H8 N2 O2
• Molecular Weight: 176.17
• Mol File: 183208-38-0.mol

Chemical Properties

• Appearance: /
• Density: 1.347g/cm³
• Refractive Index: 1.691
• CAS DataBase Reference: 1H-Pyrrolo[2,3-b]pyridine-3-carboxaldehyde, 5-methoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrolo[2,3-b]pyridine-3-carboxaldehyde, 5-methoxy-(183208-38-0)
• EPA Substance Registry System: 1H-Pyrrolo[2,3-b]pyridine-3-carboxaldehyde, 5-methoxy-(183208-38-0)

Safety Data

• Hazardous Substances Data: 183208-38-0(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
1H-Pyrrolo[2,3-b]pyridine-3-carboxaldehyde, 5-methoxyserves as a valuable building block in organic synthesis, enabling the creation of a variety of complex organic molecules. Its aldehyde group allows for a range of chemical reactions, facilitating the synthesis of diverse compounds.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 1H-Pyrrolo[2,3-b]pyridine-3-carboxaldehyde, 5-methoxyis utilized for the development of pharmaceutical compounds. Its unique structure and functional groups make it a promising candidate for the design of new drugs with potential therapeutic applications.
Used in Biological Research:
The 5-methoxy substitution on the pyridine ring of 1H-Pyrrolo[2,3-b]pyridine-3-carboxaldehyde, 5-methoxymay impart specific biological activities, making it an interesting target for biological research. 1H-Pyrrolo[2,3-b]pyridine-3-carboxaldehyde, 5-methoxycould be explored for its potential effects on biological systems and its interactions with various biomolecules.
Used in Drug Development:
Due to its potential pharmacological properties, 1H-Pyrrolo[2,3-b]pyridine-3-carboxaldehyde, 5-methoxyis a candidate for further research and development in drug discovery. Its unique features may lead to the creation of novel therapeutic agents with improved efficacy and selectivity for various medical conditions.

InChI:InChI=1/C9H8N2O2/c1-13-7-2-8-6(5-12)3-10-9(8)11-4-7/h2-5H,1H3,(H,10,11)

Upstream product

• 68-12-2 N,N-dimethyl-formamide 
• 183208-36-8 5-methoxy-1H-pyrrolo[2,3-b]pyridine 
• 183208-35-7 5-bromo-1H-pyrrolo[2,3-b]pyridine 
• 183208-32-4 3,3,5-Tribromo-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one 
• 271-63-6 7-Azaindole 
• 183208-34-6 5-bromo-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one 

Downstream Products

• 916895-89-1 7-azaserotonin 

Relevant articles and documents

NEW IMIDAZOLONE DERIVATIVES, PREPARATION THEREOF AS DRUGS, PHARMACEUTICAL COMPOSITIONS, AND USE THEREOF AS PROTEIN KINASE INHIBITORS, IN PARTICULAR CDC7

The present invention relates to imidazolone derivatives of formula (I) to methods of preparing such derivatives, intermediates thereto, pharmaceutical compositions comprising such derivatives, and methods of inhibiting protein kinase, and methods of treatment comprising administration of such derivatives.

Synthesis of 7-azaserotonin: Its photophysical properties associated with excited state proton transfer reaction

We report the synthesis of 3-(2-aminoethyl)-5-ol-1H-pyrrolo[2,3-b]pyridine (7-azaserotonin), which may potentially serve as an agonist or antagonist of serotonin receptors. In alcohols, the solvent (e.g., ethanol) catalyzed proton-transfer reaction takes place for 7-azaserotonin in the excited state, resulting in dual emission. Conversely, excited-state deprotonation takes place in neutral aqueous solution. The unique excitation behavior makes 7-azaserotonin versatile as a potential bioprobe. Copyright

PPAR ACTIVE COMPOUNDS

Compounds are described that are active on PPARs, including pan-active compounds. Also described are methods for developing or identifying compounds having a desired selectivity profile.

Synthesis of new melatoninergic ligands including azaindole moiety

A novel series of melatonin analogues, based on the azaindole nucleus is described. These compounds are prepared in several steps directly from the commercial available 7-azaindole or from substituted amino-, iodo- or/and nitropyridines using a catalysed palladium reaction or vicarious nucleophilic substitution of hydrogen (VNS) in order to elaborate the 6-, 5- and 4- azaindole derivatives respectively.