183268-72-6

Usage

Type of compound

Organic compound

Contains

Chlorine atoms and a pyrrole ring

Use in

Organic synthesis and pharmaceutical research

Type of derivative

Ketone derivative

Used in production of

Various types of drugs, including sedatives and anesthetics

Also used as

Solvent in various industrial processes

Precautions

Potential toxicity and health hazards

Upstream product

• 636-41-9 2-methyl-1H-pyrrole 
• 76-02-8 trifluoroacetyl chloride 
• 1003-29-8 2-pyrrole aldehyde 

Downstream Products

• 1194-97-4 methyl 5-methyl-1H-pyrrole-2-carboxylate 
• 848498-76-0 ethyl 4-cyano-5-methyl-1H-pyrrole-2-carboxylate 
• 25907-30-6 ethyl 4-formyl-5-methyl-1H-pyrrole-2-carboxylate 
• 25907-29-3 4-bromo-5-methyl-1H-pyrrole-2-carboxylic acid ethyl ester 
• 24691-30-3 3,4-di-chloro-5-methyl-1H-pyrrole-2-carboxylic acid 

Relevant academic research and scientific papers

PYRROLE mTORC INHIBITORS AND USES THEREOF

The present invention provides compounds, compositions thereof, and methods of using the same.

PYRROLE mTORC INHIBITORS AND USES THEREOF

The present invention provides compounds, compositions thereof, and methods of using the same.

2- (PIPERIDIN-1-YL) -4-HETEROCYCLYL-THIAZOLE-5-CARBOXYLIC ACID DERIVATIVES AGAINST BACTERIAL INFECTIONS

Compounds of formula (I) and their pharmaceutically acceptable salts are described. Processes for their preparation, pharmaceutical compositions containing them, their use as medicaments and their use in the treatment of bacterial infections are also described. Ring A is selected from formula (a), (b) or (b'):

Synthesis of 2-substituted endo-hymenialdisine derivatives

The first synthesis of 2-substituted endo-hymenialdisine derivatives 1-4 is described started with 2-substituted pyrroles and 5-substituted pyrrolo-2-carboxylic acids.

CHEMICAL COMPOUNDS

Compounds of formula (I) and their pharmaceutica11y acceptable salts are described:Processes for their preparation,pharmaceutical compositions containing them, their use as medicaments and their use in the treatment of bacterial infections are also described

ANTIBACTERIAL PIPERIDINE DERIVATIVES

Compounds of formula (I) and their pharmaceutically acceptable salts are described: Formula (I). Processes for their preparation, pharmaceutical compositions containing them, their use as medicaments and their use in the treatment of bacterial infections are also described.

TRICYCLIC DERIVATIVES OF AZETIDINE AND PYRROLE WITH ANTIBACTERIAL ACTIVITY

Compounds of formula (I) and their pharmaceutically acceptable salts are described. Processes for their preparation, pharmaceutical compositions containing them, their use as medicaments and their use in the treatment of bacterial infections are also described.

CHEMICAL COMPOUNDS

Compounds of formula (I) and their pharmaceutically acceptable salts are described: Formula (I). Processes for their preparation, pharmaceutical compositions containing them, their use as medicaments and their use in the treatment of bacterial infections are also described.

Synthesis and nucleophilic properties of 1,2 -dialkyl-3-nitropyrroles and 1,5-dialkyl-4-nitropyrrole-2-carboxylic acid derivatives

1,2-Dialkyl-3-nitropyrroles 1 are versatile synthetic tools for obtaining substituted pyrrolidines or fused ring heterocycles such as pyrrolopyridines, pyrrolopyrimidines or pyrroloazepines. We have established a method for obtaining compounds related to structure 1 and studied the reactivity as a nucleophile of the benzylic type moiety in the alkyl residue bound to position 2.