183281-86-9Relevant academic research and scientific papers
An efficient synthesis and physico-chemical properties of 2′-O-D-ribofuranosylnucleosides, minor tRNA components
Mikhailov, Sergey N.,Efimtseva, Ekaterina V.,Gurskaya, Galina V.,Fomitcheva, Marina V.,Meshkov, Sergey V.,Zavodnik, Valery E.,De Bruyn, Andre,Janssen, Gerard,Rozenski, Jef,Herdewijn, Piet
, p. 75 - 92 (2007/10/03)
A high yield preparation of 9-(2-O-β-D-ribofuranosyl-β-D-ribofuranosyl)adenine, guanine- and the pyrimidine analogs (cytosine, thymine and uracil base moiety) has been achieved, and the conformational properties of the ring systems were investigated using NMR spectroscopy and X-ray.
Synthesis of Disaccharide Nucleosides and Their Incorporation into Oligonucleotides
Efimtseva, Ekaterina V.,Ermolinsky, Boris S.,Fomitcheva, Marina V.,Meshkov, Sergei V.,Padyukova, Nelly Sh.,et al.
, p. S206 - S209 (2007/10/03)
A high yield synthesis of 2'-O-ribofuranosyl nucleosides has been achieved and incorporation of the cytosine analogue into oligonucleotides was accomplished without difficulties.The supplementary cis diol group thus present in the middle of an oligonucleotide could be easily converted to a reactive dialdehyde moiety.
