18343-31-2Relevant academic research and scientific papers
KINETICS OF FORMATION OF MONOALKOXY-s-TRIAZINES FROM CYANURIC CHLORIDE.
Marchukov,Koryakov,Lopachenok,V'yunov,Ginak
, p. 574 - 578 (2007/10/02)
2-R-alkoxy-4,6-dichloro-s-triazines (I) are used as intermediates for synthesis of herbicides, and are obtained by reactions of 2,4, 6-trichloro-s-triazine (II) (cyanuric chloride) with various alcohols in aqueous-organic mixtures in presence of hydrogen chloride acceptors. The purpose of this work was to study the quantitive relationships of the main reaction of cyanuric chloride alkoxylation and of the competing reactions of hydrolysis and alkoxylation of compound (I), for optimization of production of monoalkoxy-s-triazines. It is found that the reaction temperature has a significant influence on the yield of 2-(2-R-ethoxy)-4, 6-dichloro-s-triazine; decrease of temperature raises the yield of (I) owing to decrease of the contributions of hydrolysis of compounds (I) and (II) and alkoxylation of (I). The asolute values of the rate constants of hydrolysis (k//3, k//4) and alkoxylation (k//2) decrease more rapidly than k//1 with decrease of temperature. This makes it possible to raise the selectivity of the process by raising the alkali concentration and lowering the reaction temperature.
HALOGENATED ETHERS. XXIII. EFFECT OF TEMPERATURE AND SUBSTITUENTS ON THE KINETICS OF THE FORMATION OF 2,4-DI(2-R-ETHOXY)-6-CHLORO-sym-TRIAZINES
Marchukov, V.A.,Nikitin, O.A.,V'yunov, K.A.,Ginak, A.I.
, p. 530 - 533 (2007/10/02)
The effect of temperature and substituents on the kinetics of the reaction of 2-(2-R-ethoxy)-4,6-dichloro-sym-triazines with 2-R-ethanols in the presence of alkali was investigated.Variation of the substituent has practically no effect on the rate of hydrolysis of 2-(2-R-ethoxy)-4,6-dichloro-sym-triazines.The rate constant for the formation of 2,4-di(2-R-ethoxy)-6-chloro-sym-triazines is half that for the formation of 2-(2-R-ethoxy)-4,6-dichloro-sym-triazines.
