183434-02-8

Basic information

• Product Name: (S)-4-Ethyl-4-hydroxy-3,8-dioxo-3,4,7,8-tetrahydro-1H-pyrano[3,4-c]pyridine-6-carboxylic acid propyl ester
• Synonyms: (S)-4-Ethyl-4-hydroxy-3,8-dioxo-3,4,7,8-tetrahydro-1H-pyrano[3,4-c]pyridine-6-carboxylic acid propyl ester
• CAS NO: 183434-02-8
• Molecular Formula: C₁₄H₁₇NO₆
• Molecular Weight: 295.28788
• Mol File: 183434-02-8.mol
• Article Data: 2

Chemical Properties

• Melting Point: 187.6-189 °C
• Boiling Point: 610.6±55.0 °C(Predicted)
• Appearance: /
• Density: 1.35±0.1 g/cm3(Predicted)
• PKA: 9.19±0.60(Predicted)
• CAS DataBase Reference: (S)-4-Ethyl-4-hydroxy-3,8-dioxo-3,4,7,8-tetrahydro-1H-pyrano[3,4-c]pyridine-6-carboxylic acid propyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-4-Ethyl-4-hydroxy-3,8-dioxo-3,4,7,8-tetrahydro-1H-pyrano[3,4-c]pyridine-6-carboxylic acid propyl ester(183434-02-8)
• EPA Substance Registry System: (S)-4-Ethyl-4-hydroxy-3,8-dioxo-3,4,7,8-tetrahydro-1H-pyrano[3,4-c]pyridine-6-carboxylic acid propyl ester(183434-02-8)

Safety Data

• Hazardous Substances Data: 183434-02-8(Hazardous Substances Data)

Usage

General Description

The chemical compound "(S)-4-Ethyl-4-hydroxy-3,8-dioxo-3,4,7,8-tetrahydro-1H-pyrano[3,4-c]pyridine-6-carboxylic acid propyl ester" is a propyl ester derivative of a pyrano[3,4-c]pyridine carboxylic acid. It contains an ethyl and hydroxy group, as well as a propyl ester moiety. (S)-4-Ethyl-4-hydroxy-3,8-dioxo-3,4,7,8-tetrahydro-1H-pyrano[3,4-c]pyridine-6-carboxylic acid propyl ester may have potential pharmaceutical or medicinal applications due to its structural features, such as its ring system and carboxylic acid functionality. Further research is needed to determine the specific properties and potential uses of this compound.

Upstream product

• 99-11-6 citrazinic acid 
• 5398-44-7 2,6-dichloropyridine-4-carboxylic acid 
• 183433-68-3 5-Benzyloxymethyl-4-(2-ethyl-[1,3]dioxolan-2-yl)-6-methoxy-pyridine-2-carboxylic acid propyl ester 
• 183433-96-7 5-Benzyloxymethyl-4-((S)-1-formyl-1-hydroxy-propyl)-6-methoxy-pyridine-2-carboxylic acid propyl ester 
• 183433-72-9 5-Benzyloxymethyl-6-methoxy-4-(1-methylene-propyl)-pyridine-2-carboxylic acid propyl ester 
• 183433-67-2 3-Benzyloxymethyl-6-chloro-4-(2-ethyl-[1,3]dioxolan-2-yl)-2-methoxy-pyridine 
• 194999-55-8 (S)-4-Ethyl-3,4-dihydroxy-8-methoxy-3,4-dihydro-1H-pyrano[3,4-c]pyridine-6-carboxylic acid propyl ester 
• 183433-66-1 [6-Chloro-4-(2-ethyl-[1,3]dioxolan-2-yl)-2-methoxy-pyridin-3-yl]-methanol 
• 183433-65-0 6-Chloro-4-(2-ethyl-[1,3]dioxolan-2-yl)-2-methoxy-pyridine-3-carbaldehyde 
• 183433-64-9 6-chloro-4-(2-ethyl-1,3-dioxolan-2-yl)-2-methoxypyridine 
• 183433-63-8 2,6-dichloro-4-(2-ethyl-1,3-dioxolan-2-yl)pyridine 
• 183433-75-2 5-Benzyloxymethyl-4-((S)-1-hydroxy-1-hydroxymethyl-propyl)-6-methoxy-pyridine-2-carboxylic acid propyl ester 
• 183433-74-1 5-Benzyloxymethyl-4-(1-hydroxy-1-hydroxymethyl-propyl)-6-methoxy-pyridine-2-carboxylic acid propyl ester 
• 183433-62-7 1-(2,6-dichloropyridin-4-yl)propan-1-one 

Downstream Products

• 110351-94-5 (4S)-4-ethyl-7,8-dihydro-4-hydroxy-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione 
• 86639-52-3 7-ethyl-10-hydroxycamptothecin 
• 97682-44-5 irinotecan 

Relevant articles and documents

METHOD OF SYNTHESIZING CAMPTOTHECIN-RELATING COMPOUNDS

The present invention is to prepare efficiently 2'-amino-5'-hydroxypropiophenone corresponding to the AB-ring part of camptothecin (CPT) skeleton and a tricyclic ketone corresponding to the CDE-ring part in order to provide efficiently CPT by the total synthesis, which is a starting material for irinotecan hydrochloride and various kinds of camptothecin derivatives, and to provide stably CPT and its derivatives.