183435-05-4Relevant academic research and scientific papers
Stereospecific syntheses of 5-alkyl-3-ethoxy-2-((phenylchalcogeno)methylene)tetrahydrofurans
Yoshimatsu, Mitsuhiro,Naito, Motoyo,Shimizu, Hiroshi,Muraoka, Osamu,Tanabe, Genzoh,Kataoka, Tadashi
, p. 8200 - 8206 (2007/10/03)
2-Ethoxy-4-(phenylchalcogeno)but-3-ynyl ketones 1-10 were reduced with LiBH4 in Et2O diastereoselectively to give 5-(phenylchalcogeno)pent-4-yn-1-ols 11-20. Treatment of the phenylchalcogen-substituted alkynyl alcohols 11-20 with t-BuOK in t-BuOH provided useful (Z)-2-((phenylchalcogeno)methylene)tetrahydrofurans 21-31 stereoselectively.
