183442-67-3Relevant academic research and scientific papers
The 'unexpected' epimerization on bicyclic thiazolidine γ-lactam scaffolds
Liu, Ruzhang,Wu, Yang,Li, Qiang,Liao, Wensheng,Chen, Shu-Hui,Li, Ge,Betancort, Juan M.,Winn, David T.,Campbell, David A.
, p. 4363 - 4369 (2008/09/21)
Preliminary findings related to the base induced cyclization and spontaneous epimerization leading to stereochemically defined bicyclic thiazolidine γ-lactam systems are reported.
Secondary structure peptide mimetics: Design, synthesis, and evaluation of β-strand mimetic thrombin inhibitors
Boatman, P. Douglas,Ogbu, Cyprian O.,Eguchi, Masakatsu,Kim, Hwa-Ok,Nakanishi, Hiroshi,Cao, Bolong,Shea, J. Paul,Kahn, Michael
, p. 1367 - 1375 (2007/10/03)
Constrained dipeptide mimetic templates were designed to mimic the secondary structure of peptides in a β-strand conformation. Two templates corresponding to the D-Phe-Pro portion of the thrombin inhibitor D-Phe-Pro- ArgCH2Cl were synthesized a
