183483-09-2

Basic information

• Product Name: N-Boc-3-piperidineacetic acid
• Synonyms: 3-CARBOXYMETHYL-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER;1-BOC-PIPERIDINE-3-ACETIC ACID;2-[1-(TERT-BUTOXYCARBONYL)PIPERIDIN-3-YL]ACETIC ACID;(1-TERT-BUTOXYCARBONYL-PIPERIDIN-3-YL)-ACETIC ACID;1-N-BOC-3-PIPERIDINEACETIC ACID;BOC-1-PIPERIDINE-3-ACETIC ACID;RAC (1-TERT-BUTOXYCARBONYL-PIPERIDIN-3-YL)-ACETIC ACID;RAC (1-BOC-PIPERIDIN-3-YL)-ACETIC ACID
• CAS NO: 183483-09-2
• Molecular Formula: C₁₂H₂₁NO₄
• Molecular Weight: 243.3
• Product Categories: pharmacetical
• Mol File: 183483-09-2.mol
• Article Data: 1

Chemical Properties

• Melting Point: 76-79°C
• Boiling Point: 373 °C at 760 mmHg
• Flash Point: 179.4 °C
• Appearance: /
• Density: 1.121 g/cm³
• Vapor Pressure: 1.37E-06mmHg at 25°C
• Refractive Index: 1.486
• Storage Temp.: 2-8°C
• PKA: 4.65±0.10(Predicted)
• CAS DataBase Reference: N-Boc-3-piperidineacetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: N-Boc-3-piperidineacetic acid(183483-09-2)
• EPA Substance Registry System: N-Boc-3-piperidineacetic acid(183483-09-2)

Safety Data

• Hazard Codes: T,N
• Statements: 25-50
• Safety Statements: 45-61
• HazardClass: IRRITANT
• Hazardous Substances Data: 183483-09-2(Hazardous Substances Data)

Usage

Chemical Properties

White solid

InChI:InChI=1/C12H21NO4/c1-12(2,3)17-11(16)13-6-4-5-9(8-13)7-10(14)15/h9H,4-8H2,1-3H3,(H,14,15)

Upstream product

• 501-81-5 pyridyl-3-yl-acetic acid 
• 24424-99-5 di-tert-butyl dicarbonate 
• 74494-52-3 3-Piperidinylacetic Acid 

Downstream Products

• 309747-80-6 1-t-Butoxycarbonylpiperidine-3-ylmethylcarboxylic acid anilide 

Relevant articles and documents

Synthesis and in vitro characterization of new growth hormone secretagogues derived from ipamorelin with dipeptidomimetic N-terminals

The structural requirements for N-terminal features for the minimal structure of growth hormone secretagogues derived from ipamorelin are investigated. It is found, that incorporation of nonpolar peptidomimetic amino acids at the N-terminal can replace the Aib-His moiety and lead to compounds with high in vitro potency with respect to their growth hormone secretagogue properties. New unnatural amino acids with double bonds, ether- linkages, and 1,3-phenylene-moieties in the backbone proved to be valuable dipeptidomimetics. Using them, growth hormone secretagogues with high potencies were obtained.