183500-71-2

Upstream product

• 17201-43-3 4-cyanobenzyl bromide 
• 56481-32-4 5-bromo-2-methyl-1⁽³⁾H-imidazole-4-carbaldehyde 

Downstream Products

• 183500-72-3 1-(4-cyanobenzyl)-2-methylimidazole-5-carboxaldehyde 

Relevant academic research and scientific papers

INHIBITORS OF PRENYL-PROTEIN TRANSFERASE

The present invention comprises piperazine/piperazinone-containing compounds having multicyclic ring system substituents on one of the piperazine/piperazinone nitrogens, which inhibit prenyl-protein transferases, including farnesyl-protein transferase and geranylgeranyl-protein transferase type I. Such therapeutic compounds are useful in the treatment of cancer

INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE

The present invention is directed to compounds which inhibit farnesyl-protein transferase (FTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting farnesyl-protein transferase and the farnesylation of the oncogene protein Ras