18354-71-7

Upstream product

• 18354-70-6 1,3-dichloro-5-(toluene-4-sulfonyl)-5,6-dihydro-4H-thieno[3,4-c]pyrrole 
• 18773-54-1 4-methyl-N,N-diprop-2-ynylbenzenesulfonamide 
• 507-09-5 tiolacetic acid 
• 70-55-3 toluene-4-sulfonamide 
• 10095-90-6 ether chloromethylique au dichloromethyl-3,4-thiophene 

Relevant academic research and scientific papers

Silver-Mediated [2 + 2 + 1] Cyclization Reaction of Diynes with Elemental Selenium/Sulfur to Synthesize 3,4-Substituted Cyclopenta[ c]selenophenes/Cyclopenta[ c]thiophenes

An efficient and atom-economical silver-mediated [2 + 2 + 1] cyclization protocol for the synthesis of 3,4-fused-ring-substituted and 2,5-unsubstituted selenophenes or thiophenes has been developed. Two C-Se/C-S bonds and one C-C bond were rapidly constru

Catalytic [2+2+1] Synthesis of Fused Thiophenes Using Thiocarbonyls as Sulfur Donors

The use of N-(p-chlorophenyl)methylbenzoxazole-2-thione as a sulfur-atom donor enables the catalytic [2+2+1] cycloaddition of diynes in wet DMF at 80 °C when open to air, thus affording diverse fused thiophenes with good yields and wide functional-group c

AMINOCYCLOHEXANES AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES

The present invention is directed to novel substituted aminocyclohexanes of structural formula (I) which are inhibitors of the dipeptidyl peptidase-IV enzyme and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly Type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.

4H-THIENO[3,4-C]PYRROLE DERIVATIVES

Pyrrole derivatives of formula: STR1 in which R 1 represents a hydrogen or halogen atom, a linear or branched C 1-6 alkyl group, a C. sub.3-6 alkenyl group, a C 1-4 alkoxymethyl group, benzyl, a phenyl group optionally substituted by one or more halogen a