183544-65-2Relevant academic research and scientific papers
Synthesis of cephalosporin derivatives utilizing the cephem triflate. 1. Introduction of 3-position substituents via a cycloaddition-fragmentation route
Kang, Han-Young,Lee, Sang Hak,Choi, Kyung Il.,Koh, Hun Yeong
, p. 7549 - 7552 (1996)
An efficient synthetic route for cephalosporin derivatives with various substituents at the 3-position has been developed. It involves cycloaddition with silyl enol ethers or silylketene acetals followed by fragmentation utilizing the 3-cephem triflate 1 as a starting material.
