1836-28-8

Usage

Uses

Used in Analytical Chemistry:
DNPH is used as a reagent for detecting carbonyl compounds, such as aldehydes and ketones. It forms a colorful derivative upon reaction with these compounds, allowing for easy identification and quantification using techniques such as high performance liquid chromatography (HPLC) or gas chromatography.
Used in Environmental Monitoring:
DNPH is also used in environmental monitoring to detect and quantify carbonyl compounds in air, water, and soil samples. This helps in assessing the levels of pollutants and taking necessary measures to control them.
Used in Quality Control:
In the pharmaceutical and food industries, DNPH is used for quality control purposes to ensure the purity and safety of products. It helps in detecting the presence of unwanted carbonyl compounds that may affect the quality and safety of the products.

Upstream product

• 555-16-8 4-nitrobenzaldehdye 
• 119-26-6 (2,4-dinitro-phenyl)-hydrazine 
• 1129-37-9 4-nitrobenzaldehyde oxime 
• 32387-08-9 2-{[1-(4-Nitro-phenyl)-meth-(E)-ylidene]-amino}-isoindole-1,3-dione 
• 619-73-8 4-nitrobenzyl chloride 
• 1129-37-9 4-nitrobenzaldehyde oxime 
• 97-00-7 1-chloro-2,4-dinitro-benzene 
• 7409-30-5 p-nitrobenzylamine 

Downstream Products

• 555-16-8 4-nitrobenzaldehdye 

Relevant academic research and scientific papers

Insights into the electrooptical anion sensing properties of a new organic receptor: Solvent dependent chromogenic response and DFT studies

A highly selective hydrazine based electrooptical receptor featuring solvent based color transition properties in the presence of acetate ions has been developed. The AcO- ion mediated color transition properties of a new organic receptor in so

Synthesis, structural characterization, and antioxidant activities of 2,4-dinitrophenyl-hydrazone derivatives

Thirty-two derivatives of 2,4-dinitro phenylhydrazone 1-32 were synthesized by one step reaction and characterized by spectroscopic techniques such as EI-MS and 1H-NMR. Compounds 1-32 were screened for their in vitro antioxidant activities. DPPH radical s

Correlation analysis of reactivity in the oxidation of substituted benzyl alcohols by benzimidazolium dichromate - A kinetic and mechanistic aspects

The oxidation of a number of para- and meta-substituted benzyl alcohols by benzimidazolium dichromate (BIDC), in dimethyl sulphoxide, leads to the formation of the corresponding benzaldehydes. The reaction is first order with respect to each BIDC and alcohol. The reaction is catalyzed by hydrogen ions and the dependence has the form kobs = a + b[H+]. The oxidation of [1,1-2H2]benzyl alcohol exhibited the presence of a substantial kinetic isotope effect. The rates of the oxidation of meta-substituted benzyl alcohols correlated best with Taft's σ1 and σR0 constants. The para-substituted compounds exhibited excellent correlation with σ1 and σRBA values. The polar reaction constants are negative. The rate of oxidation of benzyl alcohol was determined in nineteen organic solvents. An analysis of the solvent effect by multiparametric equations indicated the greater importance of the cation-solvating power of the solvents. Suitable mechanisms have been discussed.

Preparation, structure, and oxidative reactivity of (dichloroiodo)pyridines: Recyclable hypervalent iodine reagents

New pyridine-based hypervalent iodine reagents, (dichloroiodo)pyridines, were prepared by chlorination of 2-, 3-, or 4-iodopyridines with NaOCl-HCl at room temperature. Structures of 2-(dichloroiodo)pyridine and 2-(dichloroiodo)-3-propoxypyridine were established by X-ray crystallography. The new (dichloroiodo)pyridines can be used as efficient reagents for oxidation of alcohols to carbonyl compounds and also as chlorinating reagents. The reduced form of the reagents such as 2-iodo-3-propoxypyridine, can be recovered from the reaction mixture in good yields by an acid-base liquid-liquid biphasic protocol.

Synthesis and antifungal activity of diaryl hydrazones from 2,4-dinitrophenylhydrazine

A new series of diarylhydrazones derived from 2,4-dinitrophenylhydrazine were synthesized via condensation with aromatic aldehydes whose structures have been determined by mass spectrometry, infrared spectroscopy, and nuclear magnetic resonance spectra. Y

Facile preparation and reactivity of polystyrene-supported (dichloroiodo)benzene: A convenient recyclable reagent for chlorination and oxidation

A facile one-pot preparation of polystyrene-supported (dichloroiodo)benzene (loading of -ICl2 up to 1.35 mmol/g) from polystyrene, iodine, and bleach has been developed. This recyclable reagent is useful for efficient chlorination of organic substrates and selective oxidation of various alcohols to the corresponding carbonyl compounds in high yields under mild conditions. The final products are conveniently separated from the polymeric byproduct by simple filtration and isolated in good purity after evaporation of solvent.

Structure-Reactivity correlation in the oxidation of substituted benzaldehydes by tetraethylammonium chlorochromate

Oxidation of 36 monosubstituted benzaldehydes by tetraethylammonium chlorochromate in dimethyl sulphoxide, leads to the formation of corresponding benzoic acids. The reaction is of first order with respect to chlorochromate and aldehydes. The reaction is promoted by H+; the H+ dependence has the form kobs = a + b[H+]. The oxidation of duteriated benzaldehyde exhibits substantial primary kinetic isotope effect. The reaction was studied in 19 different organic solvents and the effect of solvent was analyzed using Taft's and Swain's multiparametric equations. The rates of the oxidation of para- and meta-substituted benzaldehydes showed excellent correlation in terms of Charton's triparametric LDR equation, whereas the oxidation of ortho-substituted benzaldehydes were correlated well with tetraperametric LDRS equation. The oxidation of para-substituted benzaldehydes is more susceptible to the delocalized effect than is the oxidation of ortho- and meta- substituted compounds, which display a greater dependence on the field effect. The positive value of h suggests the presence of an electron-deficient reaction centre in the rate-determining step. The reaction is subjected to steric acceleration by the orthosubstituents. A suitable mechanism has been proposed.

Studies on the kinetics of tripropylammonium fluorochromate oxidation of some aromatic alcohols in non-aqueous media

The oxidation of benzyl alcohol (BnOH) and a few para-substituted benzyl alcohols by tripropylammonium fluorochromate (TriPAFC) in dimethylsulphoxide (DMSO) leads to the formation of corresponding aldehydes. The reaction is first order each in TriPAFC and the alcohols. The reaction is catalysed by hydrogen ions. The hydrogen ion dependence has the form: kobs = a + b[H +]. The oxidation of α α′-dideuterio benzyl alcohol exhibited a substantial primary kinetic isotope effect (kH/k D = 5.45 at 303 K). Oxidation of benzyl alcohol was studied in 19 different organic solvents. The solvent effect has been analysed using Kamlet's and Swain's multiparametric equation. A mechanism involving a hydride ion transfer via chromate ester is proposed.

Effect of the micellar surfactant nanoreactors on the reactions of 2,4-dinitrophenylhydrazine with some aldehydes

By thermogravimetry, the IR and electronic spectroscopy physicochemical characteristics of systems including aromatic aldehydes, 2,4- dinitrophenylhydrazine, and a surfactant were investigated. Selective solubilization effect of the cationic surfactant (c

Nitration of fullerene derivatives under mild conditions

A new family of N-(2,4-dinitrophenyl)-2-pyrazolino[60]fullerene derivatives has been synthesized by electrophilic nitration using nitronium triflate. As evidenced by CV and OSWV experiments, these species show enhanced electron-accepting properties (up to