183663-74-3Relevant academic research and scientific papers
A mild preparation of 2,6-piperidinediones
Zhu, Jiarong,Chuong, Pham Huy,Lemoine, Pascale,Tomas, Alain,Galons, Herve
, p. 1923 - 1926 (2007/10/03)
Substituted glutaric acids reacted with alkyloxyamines in the presence of M-ethyl-N-dimethylaminopropylcarbodiimide hydrochloride to form 1-alkyloxy-2,6-piperidinediones. The protecting group on the nitrogen was easily removed in high yield. This process is exemplified by the preparation of aminoglutethimide.
