183666-79-7

Basic information

• Product Name: 2,6-ditert-butyl-4-[4-(dimethylamino)benzylidene]-2,5-cyclohexadien-1-one
• Synonyms: 2,6-ditert-butyl-4-[4-(dimethylamino)benzylidene]-2,5-cyclohexadien-1-one
• CAS NO: 183666-79-7
• Molecular Formula: C₂₃H₃₁NO
• Molecular Weight: 337.49834
• Mol File: 183666-79-7.mol
• Article Data: 10

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,6-ditert-butyl-4-[4-(dimethylamino)benzylidene]-2,5-cyclohexadien-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-ditert-butyl-4-[4-(dimethylamino)benzylidene]-2,5-cyclohexadien-1-one(183666-79-7)
• EPA Substance Registry System: 2,6-ditert-butyl-4-[4-(dimethylamino)benzylidene]-2,5-cyclohexadien-1-one(183666-79-7)

Safety Data

• Hazardous Substances Data: 183666-79-7(Hazardous Substances Data)

Usage

Molecular Structure

The compound has a complex molecular structure that consists of a cyclohexadienone ring with tert-butyl substituents at the 2 and 6 positions and a dimethylamino-benzylidene group at the 4 position.

Reactivity

The presence of both aromatic and alkyl functional groups in its structure gives it a range of reactivity, making it a useful reactant in organic synthesis.

Potential Applications

2,6-ditert-butyl-4-[4-(dimethylamino)benzylidene]-2,5-cyclohexadien-1-one has potential applications in various industries, including pharmaceuticals, agrochemicals, and materials science.

Biological Activities

The compound has been studied for its potential biological activities, which could lead to the development of new and useful chemical products.

Complex Molecular Structure

The compound's complex molecular structure makes it a promising candidate for a range of applications in various industries.

Upstream product

• 619-60-3 4-(N,N-dimethylamino)phenol 
• 100-10-7 4-dimethylamino-benzaldehyde 
• 128-39-2 2,6-di-tert-butylphenol 

Relevant articles and documents

Lipase-Catalyzed Highly Efficient 1,6-Conjugated Addition for Synthesis of Triarylmethanes

Lipase from porcine pancreas (PPL) is first reported to catalyze direct 1,6-conjugated addition for synthesis of triarylmethanes using p-quinonemethides (p-QMs) and 2-naphthols. The catalytic activity of PPL was evaluated through investigating the solvent, the ratio of substrates, the enzyme loading and the temperature of the enzyme-catalyzed reactions. The present method proves to be environmentally friendly and efficient in terms of high yield, green catalyst and simple synthesis method. GraphicAbstract: [Figure not available: see fulltext.]

Silver-Catalyzed Cascade 1,6-Addition/Cyclization of para-Quinone Methides with Propargyl Malonates: An Approach to Spiro[4.5]deca-6,9-dien-8-ones

An unprecedented silver-catalyzed cascade 1,6-addition/5-exo-dig cyclization reaction between para-quinone methides and propargyl malonates under mild reaction conditions has been described. This reaction provides an efficient method to construct versatile spiro[4.5]cyclohexadienones in moderate to excellent yields with high atom economy and scalability.

Enantioselective Spirocyclopropanation of para-Quinone Methides Using Ammonium Ylides

The use of Cinchona alkaloid-based chiral ammonium ylides allows for the first highly enantioselective and broadly applicable spirocyclopropanation reactions of para-quinone methides. This strategy provides a straightforward protocol toward the chiral spiro[2.5]octa-4,7-dien-6-one skeleton, which is a frequently found structural motif in important biologically active molecules.