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DIETHYL 3-HYDROXYGLUTARATE, with the molecular formula C9H16O5, is an ester derived from 3-hydroxyglutaric acid and diethyl alcohol. It is a clear, colorless liquid characterized by a fruity odor and is soluble in water and most organic solvents. Recognized for its relatively safe chemical profile, it exhibits low toxicity and lacks known carcinogenic or mutagenic properties, although it still requires careful handling and appropriate protective measures during use.

18373-31-4

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18373-31-4 Usage

Uses

Used in Pharmaceutical Synthesis:
DIETHYL 3-HYDROXYGLUTARATE is utilized as an intermediate in the synthesis of various pharmaceutical compounds. Its chemical properties make it a valuable component in the development of new drugs, contributing to the advancement of medicinal chemistry.
Used in Food Industry as a Flavoring Agent:
In the food industry, DIETHYL 3-HYDROXYGLUTARATE serves as a flavoring agent, enhancing the taste and aroma of food products. Its fruity odor adds a pleasant and desirable scent to a range of consumables, improving the overall sensory experience for consumers.

Check Digit Verification of cas no

The CAS Registry Mumber 18373-31-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,3,7 and 3 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 18373-31:
(7*1)+(6*8)+(5*3)+(4*7)+(3*3)+(2*3)+(1*1)=114
114 % 10 = 4
So 18373-31-4 is a valid CAS Registry Number.
InChI:InChI=1/C9H16O5/c1-3-8(11)13-5-7(10)6-14-9(12)4-2/h7,10H,3-6H2,1-2H3

18373-31-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name DIETHYL 3-HYDROXYGLUTARATE

1.2 Other means of identification

Product number -
Other names 1,2,3-propanetriol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:18373-31-4 SDS

18373-31-4Downstream Products

18373-31-4Related news

Enantioselective hydrolysis of DIETHYL 3-HYDROXYGLUTARATE (cas 18373-31-4) to ethyl (S)-3-hydroxyglutarate by immobilized Candida antarctica lipase B08/27/2019

Optically pure ethyl (S)-3-hydroxyglutarate [(S)-3-EHG] is used as a key precursor for synthesis of a variety of pharmaceutically important compounds. In this work, we established an efficient procedure for enantioselectively hydrolyzing diethyl 3-hydroxyglutarate (3-DHG) to optically active (S)...detailed

18373-31-4Relevant academic research and scientific papers

Efficient and regioselective ring-opening of epoxides with carboxylic acid catalyzed by graphite oxide

Mirza-Aghayan, Maryam,Tavana, Mahdieh Molaee,Niazi, Elaheh Golam Alipour,Boukherroub, Rabah

, p. 532 - 538 (2020/07/17)

An efficient, simple and regioselective ring-opening reaction of epoxides with various carboxylic acids under metal-free conditions is reported. The ring-opening of epoxides takes place in the presence of graphite oxide as an efficient and available catalyst to produce the corresponding 2-hydroxy monoester and 1,2-diester derivatives in good yields. Regioselective attack of the nucleo-phile, short reaction times, metal-free conditions and reusability of catalyst are among the advantages of the present protocol.

Design of a highly active silver-exchanged phosphotungstic acid catalyst for glycerol esterification with acetic acid

Zhu, Shanhui,Gao, Xiaoqing,Dong, Fang,Zhu, Yulei,Zheng, Hongyan,Li, Yongwang

, p. 155 - 163 (2013/09/02)

A series of highly active, selective, and stable silver-exchanged phosphotungstic acid (AgPW) catalysts were prepared, characterized, and evaluated for bio-derived glycerol esterification with acetic acid to produce valuable biofuel additives. The structures, morphologies, acidities, and water tolerance of these samples were determined by FTIR, Raman, XRD, SEM-EDX, FT-IR of pyridine adsorption, and H2O-TPD. Several typical acidic catalysts were also performed for comparison. Among them, partially silver-exchanged phosphotungstic acid (Ag1PW) presented exceptionally high activity, with 96.8% conversion within just 15 min of reaction time and remarkable stability, due to the unique Keggin structure, high acidity as well as outstanding water-tolerance property. A plausible reaction mechanism was also proposed. In addition, this Ag1PW catalyst exhibited universal significance for esterification, holding great potential for a wide range of other acid-catalyzed reactions.

POLYOL ESTER COMPOUNDS

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Page/Page column 15, (2008/06/13)

Disclosed are polyol esters comprising a polyol having at least one hydroxyl group esterified to at least one compound having a carboxyl group. Methods of making the polyol ester compounds are also disclosed. The invention also relates to feed compositions comprising polyol ester compounds.

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