183798-89-2Relevant academic research and scientific papers
Enantio- and diastereoselective synthesis of the AB ring system of aklavinone by coupling a chemoenzymatic procedure with organometal chemistry
Banfi, Luca,Guanti, Giuseppe,Riva, Renata
, p. 13493 - 13512 (2007/10/03)
Two different approaches were investigated in order to prepare the title compound 2; best results were obtained when the tandem reduction/intramolecular hydroxyalkylation of the appropriate 5-alkoxy-(3-hydroxyphenyl)pentanoate was performed on an ester of chemoenzymatic origin, already bearing the two chiral centers present in 2 with the correct relative and absolute stereochemistry.
