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Epoxyazadiradione is a limonoid compound derived from the Neem (Azadirachta indica) plant, characterized by the presence of an epoxy group across positions 14 and 15. It is known for its insecticidal activity against mosquitoes and potential anticancer properties.

18385-59-6

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Basic information
1. Product Name: epoxyazadiradione
2. Synonyms: epoxyazadiradione
3. CAS NO:18385-59-6
4. Molecular Formula: C28H34O6
5. Molecular Weight: 466.57
6. EINECS: N/A
7. Product Categories: N/A
Chemical Properties
1. Melting Point: N/A
2. Boiling Point: 569.1°Cat760mmHg
3. Flash Point: 298°C
4. Appearance: /
5. Density: 1.25g/cm³
6. Vapor Pressure: 5.76E-13mmHg at 25°C
7. Refractive Index: 1.582
8. Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
9. Solubility: Chloroform (Slightly), Methanol (Slightly)
10. CAS DataBase Reference: epoxyazadiradione(CAS DataBase Reference)
11. NIST Chemistry Reference: epoxyazadiradione(18385-59-6)
12. EPA Substance Registry System: epoxyazadiradione(18385-59-6)
Safety Data
1. Hazard Codes: N/A
2. Statements: N/A
3. Safety Statements: N/A
4. WGK Germany:
5. RTECS:
6. HazardClass: N/A
7. PackingGroup: N/A
8. Hazardous Substances Data: 18385-59-6(Hazardous Substances Data)

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18385-59-6 Usage

Uses

Used in Anticancer Applications:
Epoxyazadiradione is used as an anticancer agent for inducing mitochondrial apoptosis and inhibiting NFkB in human cervical cancer cells. This activity suggests its potential in targeting and reducing the growth of cancer cells, making it a promising candidate for further research and development in cancer treatment.
Used in Insect Control:
In the agricultural industry, epoxyazadiradione is used as an insecticide to control mosquito populations. Its natural origin and effectiveness in targeting insects make it a valuable tool for integrated pest management strategies, helping to reduce the reliance on chemical pesticides and their associated environmental and health risks.

Check Digit Verification of cas no

The CAS Registry Mumber 18385-59-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,3,8 and 5 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 18385-59:
(7*1)+(6*8)+(5*3)+(4*8)+(3*5)+(2*5)+(1*9)=136
136 % 10 = 6
So 18385-59-6 is a valid CAS Registry Number.

InChI:InChI=1/C28H34O6/c1-15(29)33-20-13-18-24(2,3)19(30)8-10-25(18,4)17-7-11-26(5)21(16-9-12-32-14-16)22(31)23-28(26,34-23)27(17,20)6/h8-10,12,14,17-18,20-21,23H,7,11,13H2,1-6H3/t17-,18+,20?,21?,23-,25-,26?,27+,28-/m1/s1

18385-59-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name	epoxyazadiradione

1.2 Other means of identification

Product number	-
Other names	ethyl 2,3-epoxybutyrate

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:18385-59-6 SDS

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2753-30-2 gedunin

18385-59-6Related news

Diastereoselective synthesis of the model insect antifeedants related to azadiradione and epoxyazadiradione (cas 18385-59-6) based on intramolecular insertion of α-aryl-α-diazoketones08/31/2019

A new practical and stereoselective method for the synthesis of the model insect antifeedant CDE fragment of azadiradione and epoxyazadiradione, based on intramolecular insertion of α-aryl-α-diazoketones, has been developed. The procedure can be applied to complex systems. A short SAR study is...detailed

Cytotoxicity of nimbolide, epoxyazadiradione (cas 18385-59-6) and other limonoids from neem insecticide08/30/2019

Neem seed preparations contain not only azadirachtin as the active insect antifeedant or growth regulator but also a variety of other limonoids, some of which are cytotoxic to N1E-115 neuroblastoma (mouse), 143B.TK− osteosarcoma (human) and Sf9 (insect) cultured cell lines. The most potent of th...detailed

Research paperSynthesis and evaluation of anti-plasmodial and cytotoxic activities of epoxyazadiradione (cas 18385-59-6) derivatives08/29/2019

Epoxyazadiradione (1), a major compound derived from Neem oil, showed modest anti-plasmodial activity against CQ-resistant and CQ-sensitive strains of the most virulent human malaria parasite P. falciparum. A series of analogues were synthesized by modification of the key structural moieties of ...detailed

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