18391-77-0 Usage
General Description
1-methyl-3-phenyl-2-thioxoimidazolidin-4-one, also known as tioxolone, is a chemical compound with the molecular formula C10H11NO2S. It is a derivative of imidazolidine-2-thione and is commonly used in the pharmaceutical industry for its potential as an anti-inflammatory, antiviral, and antifungal agent. Tioxolone has also been studied for its potential as a treatment for acne, psoriasis, and other skin conditions. Its unique structure and properties make it a promising candidate for the development of new drugs and therapies.
Check Digit Verification of cas no
The CAS Registry Mumber 18391-77-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,3,9 and 1 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 18391-77:
(7*1)+(6*8)+(5*3)+(4*9)+(3*1)+(2*7)+(1*7)=130
130 % 10 = 0
So 18391-77-0 is a valid CAS Registry Number.
18391-77-0Relevant articles and documents
Synthesis and biological evaluation of 3-substituted 5-benzylidene-1-methyl-2-thiohydantoins as potent NADPH oxidase (NOX) inhibitors
Bae, Yun Soo,Choi, Sun,Park, Jung Jae,Joo, Jung Hee,Cui, Minghua,Cho, Hyunsung,Lee, Won Jae,Lee, Sang Hyup
, p. 4144 - 4151 (2016/08/23)
We report the synthesis of novel 3-substituted 5-benzylidene-1-methyl-2-thiohydantoins 3, and their biological evaluation using NADPH oxidase (NOX) 1 and 4. Based on structural and pharmacophore analyses of known inhibitors such as hydroxypyrazole 2, we e
Synthesis of 3-substituted 5-arylidene-1-methyl-2-Thiohydantoins under microwave irradiation
Khodair, Ahmed I.,Nielsen, John
, p. 1017 - 1032 (2007/10/03)
A mono-modal microwave oven was used to expedite the synthesis of small libraries of 3-substituted 1-methyl-2-thiohydantoins and 3-substituted 5-arylidene-1-methyl-2-thiohydantoins. In comparison with the traditional reflux methods, similar or higher yields were obtained.
