18392-47-7

Basic information

• Product Name: Ethanol, 2-(2-benzothiazolylamino)- (7CI,8CI,9CI)
• Synonyms: Ethanol, 2-(2-benzothiazolylamino)- (7CI,8CI,9CI);2-(1,3-benzothiazol-2-ylamino)-1-ethanol
• CAS NO: 18392-47-7
• Molecular Formula: C₉H₁₀N₂OS
• Molecular Weight: 194.2535
• Product Categories: BENZOTHIAZOLE
• Mol File: 18392-47-7.mol
• Article Data: 7

Chemical Properties

• Melting Point: 102-104°
• Boiling Point: 357.6 °C at 760 mmHg
• Flash Point: 170 °C
• Appearance: /
• Density: 1.39 g/cm³
• Vapor Pressure: 9.83E-06mmHg at 25°C
• Refractive Index: 1.739
• CAS DataBase Reference: Ethanol, 2-(2-benzothiazolylamino)- (7CI,8CI,9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanol, 2-(2-benzothiazolylamino)- (7CI,8CI,9CI)(18392-47-7)
• EPA Substance Registry System: Ethanol, 2-(2-benzothiazolylamino)- (7CI,8CI,9CI)(18392-47-7)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 18392-47-7(Hazardous Substances Data)

Usage

General Description

Ethanol, 2-(2-benzothiazolylamino)- (7CI,8CI,9CI) is a chemical compound with the molecular formula C20H17N3OS. It is a derivative of benzothiazole, a heterocyclic aromatic compound. This chemical is commonly used in the production of dyes, pharmaceuticals, and agricultural chemicals. It is also used as a fluorescent tracer in biochemical and biochemical research. The compound may have potential applications in the development of new materials and in pharmacology. However, it is important to handle this chemical with care, as it may pose health and environmental risks if not properly managed.

InChI:InChI=1/C9H10N2OS/c12-6-5-10-9-11-7-3-1-2-4-8(7)13-9/h1-4,12H,5-6H2,(H,10,11)

Upstream product

• 103-72-0 phenyl isothiocyanate 
• 141-43-5 ethanolamine 
• 615-20-3 2-chlorobenzo[d][1,3]thiazole 
• 65902-53-6 potassium benzothiazole-2-sulfonate 
• 102-12-5 N-2-hydroxyethyl-N'-phenylthiourea 
• 18226-14-7 benzothiazole-2-sulfonic acid 2-hydroxy-ethylamide 

Downstream Products

• 22258-71-5 3-(β-chloroethyl)benzothiazolin-2-one 
• 75105-02-1 N-(2-chloroethyl)-1,3-benzothiazol-2-amine 

Relevant articles and documents

Unexpected reactivity of annulated 3H-benzothiazol-2-ylideneamines as an acyl transfer catalyst

Catalytic ability of annulated 3H-benzothiazol-2-ylideneamines and 1H-pyridin-2-ylideneamines for acylation of alcohols was investigated and 3,4-dihydro-2H-9-thia-1,4a-diazafluorene (2b) was found to be an extremely effective catalyst, the reaction with which was faster than that with DMAP.

Convenient and reliable routes towards 2-aminothiazoles: Palladium-catalyzed versus copper-catalyzed aminations of halothiazoles

Two efficient methods for the amination of 2-halothiazoles are presented here. A first protocol requires a Pd/L system. Several 2-aminothiazoles were synthesized under optimized conditions and isolated in good yields. The first palladium-catalyzed C-N coupling reactions between 2-halothiazoles and primary alkylamines are presented. In a second part, ligand-free copper-catalyzed aminations of 2-halothiazoles by alkylamines and aniline in a green solvent have been developed. The protocol is very effective for primary and secondary amines and perfectly tolerates the presence of another halide moiety on the 2-halothiazole. The reaction occurs under the assistance of microwave irradiation, which drastically decreases the reaction time. The reaction leads to the formation of 2-aminothiazoles, key molecules in pharmaceutical research. Copyright

One-pot synthesis of 2-aminobenzothiazoles using a new reagent of [Bmim]Br3 in [Bmim]BF4

The one-pot direct synthesis of 2-aminobenzothiazoles from phenyl isothiocyanate and amines using a new reagent of 1-butyl-3-methylimidazolium tribromide ([Bmim]Br3) in ionic liquid 1-butyl-3-methyl-imidazolium tetraflouoroborate ([Bmim]BF4) is described.