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2,6-mansyl chloride, also known as 2,6-dimethoxy-4-methylsulfonyl chloride, is a chemical compound often used in organic synthesis as a protecting group for amines. It is a derivative of methanesulfonyl chloride, with the two methoxy groups attached to the 2 and 6 positions of the benzene ring. This versatile reagent can be used to selectively protect primary and secondary amines in the presence of other functional groups, making it an important tool in organic chemistry for the preparation of a wide range of biologically active compounds.

18392-55-7

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18392-55-7 Usage

Uses

Used in Pharmaceutical Synthesis:
2,6-mansyl chloride is used as a protecting agent for amines in the synthesis of pharmaceuticals. It allows chemists to temporarily block the reactivity of specific amine groups while carrying out other chemical reactions, ensuring that the desired product is formed without unwanted side reactions.
Used in Organic Chemistry Research:
2,6-mansyl chloride is used as a selective protecting agent for amines in the preparation of complex organic molecules. Its ability to protect primary and secondary amines in the presence of other functional groups makes it a valuable reagent in the synthesis of biologically active compounds, facilitating the development of new drugs and other chemical entities.
Used in Drug Delivery Systems:
2,6-mansyl chloride is used as a component in the design of drug delivery systems, where it can be employed to protect amine groups in drug molecules during the synthesis of drug carriers or conjugates. This protection can help to improve the stability and bioavailability of the drug, as well as to enable targeted delivery to specific tissues or cells.

Check Digit Verification of cas no

The CAS Registry Mumber 18392-55-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,3,9 and 2 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 18392-55:
(7*1)+(6*8)+(5*3)+(4*9)+(3*2)+(2*5)+(1*5)=127
127 % 10 = 7
So 18392-55-7 is a valid CAS Registry Number.
InChI:InChI=1/C17H14ClNO2S/c1-19(15-5-3-2-4-6-15)16-9-7-14-12-17(22(18,20)21)10-8-13(14)11-16/h2-12H,1H3

18392-55-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name 6-(N-methylanilino)naphthalene-2-sulfonyl chloride

1.2 Other means of identification

Product number -
Other names Mansyl compounds

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:18392-55-7 SDS

18392-55-7Relevant academic research and scientific papers

INTRAMOLECULAR DONOR-ACCEPTOR SYSTEMS. Part 8. Solvent and substituent effects on the fluorescence emission of 6-N-methyl-N-phenylamino-2-naphthalenesulfon-N,N-dimethylamides

Kosower, Edward M.,Kanety, Hannah

, p. 259 - 268 (2007/10/02)

The dual fluorescence (emissions from S1,np and S1,ct states) of N-phenylaminonaphthalenesulfonate (ANS) systems is briefly reviewed.The 6-N-methyl-N-phenylamino-2-naphthalenesulfon-N,N-dimethylamides also exhibit dual fluorescence, as shown by plots of emission energy and ΦF against the sovent polarity parameter, ET(30).The solvent polarities, for which appearance of S1,ct emission marks the occurence of an intramolecular electron transfer (i.e.t.) process, are appreciably lower than those of the corresponding sulfonates.The fluorescence of the dimethylamides exhibits a high sensitivity to substituent change, the apparent Hammett ρ value being ca. -13 for unsubstituted dimethylamide and -33 for N-methyl-substituted dimethylamide.The N,N-dimethylamides are particularly suitable for the investigation of the rates and mechanisms of intramolecular electron-transfer processes by picosecond and nanosecond pulse techniques.

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