183960-82-9

Upstream product

• 80522-42-5 triisopropylsilyl trifluoromethanesulfonate 
• 211187-45-0 (4R)-4-benzyl-3-((2R,3S,4S,5R)-3,5-dihydroxy-2,4-dimethyl-1-oxohexyl)-2-oxazolidinone 
• 184178-78-7 (4R)-4-benzyl-3-((2R,4S,5R)-5-hydroxy-2,4-dimethyl-1,3-dioxohexyl)-2-oxazolidinone 
• 101712-01-0 (R)-1-((R)-4-benzyl-2-oxooxazolidin-3-yl)-2-methylpentane-1,3-dione 
• 79271-56-0 triethylsilyl trifluoromethyl sulfonate 
• 183960-62-5 (R)-4-Benzyl-3-((2R,3S,4R,5R)-3-hydroxy-2,4-dimethyl-5-triisopropylsilanyloxy-hexanoyl)-oxazolidin-2-one 

Downstream Products

• 211187-44-9 (R)-2-[(2S,4S,5R,6S)-6-((S)-2-{(R)-2-[(1S,2R,3S,4R,5R)-1-(tert-Butyl-dimethyl-silanyloxy)-3-hydroxy-2,4-dimethyl-5-triisopropylsilanyloxy-hexyl]-oxiranyl}-1-methyl-ethyl)-5-methyl-2-phenyl-[1,3]dioxan-4-yl]-propionic acid 
• 183960-69-2 (R)-4-Benzyl-3-{(R)-2-[(2S,4S,5R,6S)-6-((1S,4S,5R,6R,7R,8R)-4,6-dihydroxy-1,5,7-trimethyl-3-methylene-8-triisopropylsilanyloxy-nonyl)-5-methyl-2-phenyl-[1,3]dioxan-4-yl]-propionyl}-oxazolidin-2-one 
• 211187-40-5 (R)-4-Benzyl-3-[(R)-2-((2S,4S,5R,6S)-6-{(S)-2-[(R)-2-((1S,2R,3R,4R,5R)-1,3-dihydroxy-2,4-dimethyl-5-triisopropylsilanyloxy-hexyl)-oxiranyl]-1-methyl-ethyl}-5-methyl-2-phenyl-[1,3]dioxan-4-yl)-propionyl]-oxazolidin-2-one 
• 183960-89-6 (R)-4-Benzyl-3-{(R)-2-[(2S,4S,5R,6S)-6-((1S,5R,6S,7R,8R)-6-hydroxy-1,5,7-trimethyl-3-methylene-4-oxo-8-triisopropylsilanyloxy-nonyl)-5-methyl-2-phenyl-[1,3]dioxan-4-yl]-propionyl}-oxazolidin-2-one 
• 211187-42-7 (R)-4-Benzyl-3-{(R)-2-[(2S,4S,5R,6S)-6-((S)-2-{(R)-2-[(1S,2R,3S,4R,5R)-1-(tert-butyl-dimethyl-silanyloxy)-3-hydroxy-2,4-dimethyl-5-triisopropylsilanyloxy-hexyl]-oxiranyl}-1-methyl-ethyl)-5-methyl-2-phenyl-[1,3]dioxan-4-yl]-propionyl}-oxazolidin-2-one 
• 183960-68-1 (R)-4-Benzyl-3-{(R)-2-[(2S,4S,5R,6S)-5-methyl-2-phenyl-6-((1S,5R,6S,7S,8R)-1,5,7-trimethyl-3-methylene-4-oxo-6-triethylsilanyloxy-8-triisopropylsilanyloxy-nonyl)-[1,3]dioxan-4-yl]-propionyl}-oxazolidin-2-one 

Relevant academic research and scientific papers

General strategies toward the syntheses of macrolide antibiotics. The total syntheses of 6-deoxyerythronolide B and oleandolide

The asymmetric syntheses of 6-deoxyerythronolide B (1) and oleandolide (2) have been achieved, each in 18 linear steps. These syntheses demonstrate the utility of chiral β-keto imide building block 3 as a versatile building block for the aldol-based assemblage of polypropionate-derived natural products.