183989-82-4Relevant academic research and scientific papers
Regio- and chemoselective n-1 acylation of indoles: Pd-catalyzed domino cyclization to afford 1,2-fused tricyclic indole scaffolds
Liu, Yongxian,Huang, Yuanqiong,Song, Hongjian,Liu, Yuxiu,Wang, Qingmin
supporting information, p. 5337 - 5340 (2015/03/30)
A concise method for the synthesis of 1,2-fused tricyclic indole scaffolds by domino cyclization involving a Pd-catalyzed Sonogashira coupling, indole cyclization, regio- and chemoselective N-1 acylation, and 1,4-Michael addition is reported. This method
Self-induced stereoselective in situ trifluoromethylation: Preparation of spiro[indoline-3,3′-quinoline] via palladium-catalyzed cascade reaction
Song, Hongjian,Liu, Yongxian,Liu, Yuxiu,Wang, Qingmin
supporting information, p. 3240 - 3243 (2014/07/08)
An efficient method to prepare 1′H-spiro[indoline-3,3′- quinoline]-2′,4′-diones and their trifluoromethylated products was developed via a palladium-catalyzed Sonogashira coupling/Wacker-type oxypalladation/cyclization cascade reaction. The amount of wate
INDOLE AND AZAINDOLE MODULATORS OF THE ALPHA 7 NACHR
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Page/Page column 51, (2011/05/05)
This invention relates to modulation of the α7 nicotinic acetylcholine receptor (nAChR) by a compound of formula (I) or a pharmaceutically acceptable salt thereof.
INDOLES AS MODULATORS OF NICOTINIC ACETYLCHOLIN RECEPTOR SUBTYPE ALPHA-71
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Page/Page column 37, (2009/12/02)
This invention relates to modulation of the α7 nicotinic acetylcholine receptor (nAChR) by a compound of formula (I) or a salt thereof: Formula (I)
Synthesis of indoles and quinolones by sequential Wittig and Heck reactions
Latham, Elliot J.,Stanforth, Stephen P.
, p. 2059 - 2063 (2007/10/03)
Trifluoroacetamido derivatives 18a-c and 19a-c react with phosphorane 2 in boiling toluene to give the corresponding enamines 12a-c and 13a-c respectively which are precursors of the trifluoromethylated indoles 14a-c and quinolones 15a-c.
