183995-72-4Relevant articles and documents
Isothiocyanate-Directed Ortho-Selective Halogenation of Arenes via C–H Functionalization
Mandapati, Usharani,Pinapati, Srinivasarao,Tamminana, Ramana,Rameshraju, Rudraraju
, p. 418 - 423 (2017/11/29)
Abstract: Ortho-selective halogenation of arenes via C–H functionalization has been described under mild reaction conditions. In this reaction Cu(II)X2 was used as a halide source. It is a simple, general and efficient method for the synthesis of 2-halo aromatic isothiocyanates. All the reactions are carried out under optimized reaction conditions to provide their respective desired products in good to high yield. Graphical Abstract: We have developed a general, simple and efficient method for the synthesis of 2-halo arylisothiocyanates from isothiocyanates through ortho-selective halogenation under mild reaction conditions. Cu(II)X2 was used as a halide source for this methodology. All the reactions are carried out under optimized reaction conditions to provide their respective desired products in good to high yield. [Figure not available: see fulltext.].