184-26-9

Usage

Uses

Used in Pharmaceutical Industry:
Cycloheptanone ethylene ketal is used as a key intermediate in the synthesis of various medications, contributing to the development of new pharmaceutical products.
Used in Agrochemical Industry:
In the agrochemical sector, cycloheptanone ethylene ketal serves as a crucial component in the production of crop protection products, enhancing agricultural productivity and crop safety.
Used in Flavor and Fragrance Industry:
Cycloheptanone ethylene ketal is employed in the creation of flavor and fragrance compounds, adding unique scents and tastes to various consumer products.
Used in Polymer and Resin Production:
CYCLOHEPTANONE ETHYLENE KETAL is also utilized in the synthesis of polymers and resins, contributing to the development of new materials with specific properties for various applications.

InChI:InChI=1/C9H16O2/c1-2-4-6-9(5-3-1)10-7-8-11-9/h1-8H2

Upstream product

• 107-21-1 ethylene glycol 
• 502-42-1 cycloheptanone 
• 75-21-8 oxirane 
• 176-32-9 1,4-dioxaspiro[4.4]nonane 
• 177-10-6 1,3-dioxolane-2-spirocyclohexane 
• 118247-58-8 2-(Bicyclo[4.1.0]hept-1-yloxy)-ethanol 
• 1121-49-9 bromomethylenecyclohexane 
• 23904-33-8 (iodomethylene)cyclohexane 

Downstream Products

• 502-42-1 cycloheptanone 
• 184-32-7 1,4-dithia-spiro[4.6]undecane 
• 3349-73-3 cycloheptanone 2,4-dinitrophenylhydrazone 
• 41330-04-5 6,11-dibromo-1,4-dioxa-spiro[4.6]undecane 
• 1728-32-1 1-methoxycyclohepta-1,3,5-triene 
• 1121-65-9 cyclohepta-3,5-dienone 
• 39124-95-3 2-[1-(4-Chloro-phenyl)-cycloheptyloxy]-ethanol 
• 40929-86-0 2-(1-Phenethyl-cycloheptyloxy)-ethanol 
• 22657-01-8 2-(1-Benzyl-cycloheptyloxy)-ethanol 

Relevant academic research and scientific papers

One-pot synthesis of ordered mesoporous zirconium oxophosphate with high thermostability and acidic properties

A series of mesoporous zirconium oxophosphate (M-ZrPO) with different P/Zr molar ratios (0-1.25) has been prepared via a facile one-pot evaporation-induced self-assembly (EISA) strategy. After removing the structure-directing agents, the M-ZrPO with large specific surface area (160 m2 g-1), big pore volume (0.26 cm3 g-1) and narrow pore size distribution (5.64 nm) has been obtained. Small-angle X-ray diffraction (SXRD) and transmission electron microscopy (TEM) results showed that these materials had ordered mesoporous structure. With the increase of P/Zr, the textural properties of M-ZrPO could be improved. Moreover, the ordered mesostructure could be maintained even when treated at 800°C, indicating the M-ZrPO had attractive thermal stability. NH3-TPD and pyridine-IR analyses showed the presence of abundant Broensted and Lewis acid sites in the material. The M-ZrPO has been used successfully as solid acid catalyst and showed excellent performance in the ketalization reaction.

A mild, room-temperature protection of ketones and aldehydes as 1,3-dioxolanes under basic conditions

Protection of ketones or aldehydes as 1,3-dioxolane derivatives proceeds within minutes at room temperature in the presence of N- hydroxybenzenesulfonamide, its O-benzyl derivative, or the tosyl analogue, in the absence of strong protonic acids, and in the presence of base (Et). Acid-sensitive groups such as O-THP, O-TBS, or N-Boc are unaffected. Copyright

Synthesis of phototrappable shape-shifting molecules for adaptive guest binding

We have designed and synthesized oligosubstituted bullvalenes 1 and 2 as adaptive molecules that can change their shapes in order to bind tightly to a suitable guest. By incorporation of a photolabile o-nitroveratryloxycarbonate (NVOC) group into bullvalenes 1 and 2, tightly binding species can be selectively isolated from a population of hundreds of interconverting structural isomers. Spontaneous strain-assisted Cope rearrangements allow these shape-shifting molecules to exist in a dynamic equilibrium of configurationally distinct valence isomers, as revealed by dynamic NMR and HPLC studies. When NVOC bullvalenes 1 and 2 were exposed to UV light, the cleavage of the NVOC group resulted in a mixture of static isomers of the corresponding bullvalone. Binding studies of NVOC bisporphyrin bullvalene 1 demonstrated that the dynamic isomeric equilibrium shifted in the presence of C60, favoring configurations with more favorable binding affinities. Irradiation of a mixture of 1 and C60 with UV light and isolation of the major static isomer yielded an isomer of bisporphyrin bullvalone with a binding affinity for C 60 that was ～2 times larger than that of the nonadapted isomer bisporphyrin bullvalone 41.

Correlation between 13C and 17O chemical shifts and torsional strain in spiroacetals

The relationship between the 13C and 17O NMR chemical shifts and the dihedral energies (non-bonding interactions) of 1,4-dioxaspiro[4.4]nonane, 1,4-dioxa- and 6,10-dioxaspiro[4.5]decane, 1,4-dioxa- and 6,11-dioxaspiro[4.6]undecane, 1,5-dioxaspiro[5.5]undecane, 1,5-dioxa and 7,12-dioxaspiro[5.6]dodecane and 1,6-dioxaspiro[6.6]tridecane were analyzed. These data showed correlation of the non-bonding interactions with the chemical shift of the spiranic carbon, as well as a linear relationship between 13C and 17O.

A simple and practical synthetic protocol for acetalisation, thioacetalisation and transthioacetalisation of carbonyl compounds under solvent-free conditions

A wide variety of carbonyl compounds can be converted smoothly to the corresponding acetals on treatment with alcohols or diols and triethyl orthoformate in the presence of a catalytic amount of (bromodimethyl)sulfonium bromide at room temperature. Similarly, various carbonyl compounds can be transformed into the corresponding dithioacetals on reaction with thiol or dithiols at room temperature by employing the same catalyst without any solvent. Moreover, O,O-acetals can also be converted into the corresponding dithioacetals under identical conditions. Some of the major advantages are mild reaction conditions, a high degree of efficiency, compatibilty with other protecting groups and the lack of solvents, particularly for thioacetalisation. In addition, no brominations occur at the double bond or α to the keto position or even in the aromatic ring under these experimental conditions. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004.

Eco-friendly Pt-Mo/ZrO2 solid acid catalyst for selective protection of carbonyl compounds

An easy method for protection of carbonyl compounds has been carried out in excellent yields under catalysis of Pt-Mo/ZrO2 in toluene at 383 K.

1,3-Dioxolanes from carbonyl compounds over zeolite HSZ-360 as a reusable, heterogeneous catalyst

Carbonyl compounds are converted, in good yields, into their 1,3-dioxolanes over zeolite HSZ-360, as a new reusable catalyst. Good chemoselectivity is also observed.

Microwave-assisted acetalization of carbonyl compounds catalyzed by reusable Envirocat supported reagents

Envirocat supported reagents (EPZG, EPZ10, and EPIC) are found to efficiently catalyze the acetalization of carbonyl compounds with 1,2-ethanediol under microwave irradiation under solvent-free conditions. The reagents can be used in repeated experiments to perform the reaction with the same activity.

Microwave promoted acetalization of aldehydes and ketones

Aldehydes and ketones are readily acetalized under microwave irradiation with ethylene glycol in the presence of p-toluenesulfonic acid(PTSA), ferric(III) chloride or acidic alumina.