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2,2,4-trimethyl-7-(1,1,3,3-tetramethylbutyl)chroman-6-ol, commonly known as Trolox, is a water-soluble analogue of vitamin E. It is a potent antioxidant capable of neutralizing free radicals and safeguarding cells from oxidative stress. Trolox has garnered significant attention for its potential health benefits, which encompass protection against cardiovascular disease, cancer, and neurodegenerative disorders. Its antioxidant and anti-inflammatory properties also make it a valuable component in cosmetics and pharmaceuticals, with demonstrated anti-aging effects and contributions to skin health promotion.

18403-59-3

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18403-59-3 Usage

Uses

Used in Health and Nutritional Supplements:
2,2,4-trimethyl-7-(1,1,3,3-tetramethylbutyl)chroman-6-ol is used as a dietary supplement for its antioxidant properties to support overall health and well-being by combating oxidative stress and potentially reducing the risk of various diseases.
Used in Pharmaceutical Applications:
In the pharmaceutical industry, 2,2,4-trimethyl-7-(1,1,3,3-tetramethylbutyl)chroman-6-ol is used as an active ingredient in medications aimed at treating conditions associated with oxidative stress, such as cardiovascular diseases and neurodegenerative disorders, due to its ability to protect cells from damage.
Used in Cosmetics:
2,2,4-trimethyl-7-(1,1,3,3-tetramethylbutyl)chroman-6-ol is used as an ingredient in cosmetic products for its antioxidant and anti-inflammatory properties, which can help in reducing signs of aging and promoting skin health.
Used in Research:
In scientific research, 2,2,4-trimethyl-7-(1,1,3,3-tetramethylbutyl)chroman-6-ol is used as a standard compound in assays to evaluate the antioxidant capacity of other substances, given its well-established antioxidant activity.

Check Digit Verification of cas no

The CAS Registry Mumber 18403-59-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,4,0 and 3 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 18403-59:
(7*1)+(6*8)+(5*4)+(4*0)+(3*3)+(2*5)+(1*9)=103
103 % 10 = 3
So 18403-59-3 is a valid CAS Registry Number.
InChI:InChI=1/C20H32O2/c1-13-11-20(7,8)22-17-10-15(16(21)9-14(13)17)19(5,6)12-18(2,3)4/h9-10,13,21H,11-12H2,1-8H3

18403-59-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name 2,2,4-trimethyl-7-(2,4,4-trimethylpentan-2-yl)-3,4-dihydrochromen-6-ol

1.2 Other means of identification

Product number -
Other names 2,2,4-Trimethyl-7t-octyl-6-hydroxychroman

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:18403-59-3 SDS

18403-59-3Downstream Products

18403-59-3Relevant academic research and scientific papers

A GENERAL METHOD FOR THE PREPARATION OF 2,2,4-TRIMETHYL AND 2,2-DIMETHYL-4-ISOPROPYL-6-HYDROXY-7-SUBSTITUTED CHROMANS

Eubanks, J. R. I.,Pacifici, J. G.

, p. 829 - 836 (2007/10/02)

2,2,4-Trimethyl and 2,2-dimethyl-4-isopropyl-6-hydroxy-7-substituted chromans can be conveniently prepared by the reaction of 2-substituted hydroquinones with 2-methyl-2,4-pentanediol or 2,5-dimethyl-2,5-hexanediol, respectively, in the presence of macroreticular strongly acidic sulfonic acid cation exchange resin catalysts.The reaction is positionally selective and allows for simple workups and reasonable yields.

Process for producing 2,2,4-trimethyl-6-hydroxy-7-substituted chromans

-

, (2008/06/13)

A process for producing 2,2,4-trimethyl-6-hydroxy-7-substituted chromans which comprises reacting 2-substituted hydroquinones with 2-methyl-2,4-pentanediol in the presence of a Friedel-Crafts catalyst.

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