1841079-88-6

Basic information

• Product Name: 3-(1H-pyrrolo[2,3-c]pyridin-1-yl)isoquinolin-5-amine
• CAS NO: 1841079-88-6
• Molecular Weight: 260.298
• Mol File: 1841079-88-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(1H-pyrrolo[2,3-c]pyridin-1-yl)isoquinolin-5-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(1H-pyrrolo[2,3-c]pyridin-1-yl)isoquinolin-5-amine(1841079-88-6)
• EPA Substance Registry System: 3-(1H-pyrrolo[2,3-c]pyridin-1-yl)isoquinolin-5-amine(1841079-88-6)

Safety Data

• Hazardous Substances Data: 1841079-88-6(Hazardous Substances Data)

Upstream product

• 58142-49-7 3-chloro-5-amino-isoquinoline 
• 10296-47-6 3-chloro-5-nitro-isoquinoline 
• 19493-45-9 3-chloroisoquinoline 

Relevant articles and documents

PYRROLO[2,3-C]PYRIDINES AS IMAGING AGENTS FOR NEUROFIBRILARY TANGLES

Pyrrolopyridine compounds of formula (I) or their pharmaceutically acceptable salts are disclosed, which may be suitable for imaging tau aggregates, b-sheet aggregates, beta-amyloid aggregates or alpha- synuclein aggregates, and hence are useful in binding and imaging tau aggregates in Alzheimer's patients. More specifically, the compounds are used as tracers in positron emission tomography (PET) imaging to study tau deposits in brain in vivo to allow diagnosis of Alzheimer's disease and other neurodegenerative diseases characterized by tau pathology. Futher, the compounds are useful for measuring clinical efficacy of therapeutic agents for Alzheimer's disease and other neurodegenerative diseases characterized by tau pathology.