184178-86-7Relevant academic research and scientific papers
One-Pot Synthesis of N-tert-Butylsulfinylimines and Homoallylamine Derivatives from Epoxides
Lahosa, Alejandro,Foubelo, Francisco,Yus, Miguel
supporting information, p. 4067 - 4076 (2016/08/24)
The reaction of epoxides with tert-butanesulfinamide in the presence of a Lewis acid, such as erbium triflate or boron trifluoride–diethyl ether, in THF as solvent, under microwave or thermal activation, produces N-tert-butylsulfinylimines in reasonable yields. Aromatic and gem-disubstituted and trisubstituted alkyl epoxides performed better than mono-alkyl-substituted compounds. After imine formation, a subsequent indium-promoted allylation can be carried out in the same reaction flask in a single synthetic operation leading to homoallylamine derivatives with generally high yields.
Process for making neo-enriched p-menthane compounds
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Page/Page column 11, (2012/05/20)
A process for making neo-enriched p-menthane intermediates is disclosed. Lewis acid-catalyzed rearrangement of an oxaspiro compound provides an aldehyde mixture comprising normal (II) and neo (III) p-menthane-3-aldehydes: with the neo aldehyde (III) as the major product. The aldehyde mixture is readily oxidized to provide the corresponding carboxylic acids, and the acids are easily converted to a host of neo-enriched p-menthane esters or amides. The esters and amides are valuable as physiological coolants.
Synthesis and characterization of a new enantiopure hydroxylated phosphine, its rhodium(I) and (III) complexes and their performance in catalytic carbonylation
Duran, Josep,Oliver, Daniel,Polo, Alfonso,Real, Julio,Benet-Buchholz, Jordi,Fontrodona, Xavier
, p. 2529 - 2538 (2007/10/03)
The enantiomerically pure hydroxylated phosphine (1S,2S,5R)-1-diphenylphosphinomethyl-2-isopropyl-5-methyl-cyclohexanol 3 was prepared in a two-step stereoselective process from the commercially available and low cost (-)-menthone. Reaction of this new li
