184292-96-4Relevant academic research and scientific papers
Synthesis and biological activity of conformationally restricted analogs of milnacipran: (1S,2A)-1-Phenyl-2-[(S)-1-aminopropyl]-N,N-diethylcyclopropanecarboxamide, an efficient noncompetitive N-methyl-D-aspartic acid receptor antagonist
Shuto, Satoshi,Ono, Shizuka,Hase, Yukako,Ueno, Yoshihito,Noguchi, Tomohiro,Yoshii, Kiyonori,Matsuda, Akira
, p. 4844 - 4852 (2007/10/03)
We recently demonstrated that (±)-(Z)-2-(aminomethyl)-1-phenyl-N,N-diethylcyclopropanecarboxamide [milnacipran, (±)-1], an inhibitor of the reuptake of serotonin (5-HT), was a noncompetitive NMDA receptor antagonist. On the basis of the cyclopropane struc
